IQGAP3 and CCDC198

Number of citations of the paper that reports this interaction (PubMedID 27107012)
40

Data Source:
BioGRID (two hybrid)

		IQGAP3	CCDC198
Description		IQ motif containing GTPase activating protein 3	coiled-coil domain containing 198
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cell-cell Junction Lateral Plasma Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Calmodulin Binding Small GTPase Binding Actin Filament Binding Myosin VI Light Chain Binding	Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Phosphorylation Ras Protein Signal Transduction Regulation Of Cell Size Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Mammary Gland Epithelial Cell Proliferation Regulation Of GTPase Activity Positive Regulation Of MAPK Cascade ERK1 And ERK2 Cascade Cellular Response To Organic Substance
Pathways		RHO GTPases activate IQGAPs RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle
Drugs
Diseases
GWAS		Adult body size ( 32376654) Creatine kinase levels ( 29403010)
Interacting Genes		2 interacting genes: CALM2 CCDC198	27 interacting genes: CBY2 FAM9B FHL2 FHL3 FKBP6 GOLGA2 GOPC HOOK2 HSF2BP IQGAP3 KIFC3 KRT31 KRT34 KRT40 LZTS2 MDFI MTUS2 PDE4DIP PFDN5 PNMA1 SIAH1 SMAD3 SSX2IP TEX11 TRAF1 TRAF2 TRIM27
Entrez ID		128239	55195
HPRD ID		11051	12628
Ensembl ID		ENSG00000183856	ENSG00000100557
Uniprot IDs		Q86VI3	B7ZL43 E9PSE9 F5GWJ3 Q05C89 Q9NVL8
PDB IDs		3ISU
Enriched GO Terms of Interacting Partners?
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