IQGAP3

Description		IQ motif containing GTPase activating protein 3
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GO Annotations	Cellular Component	Cytoplasm Cytosol Cell-cell Junction Lateral Plasma Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Calmodulin Binding Small GTPase Binding Actin Filament Binding Myosin VI Light Chain Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Phosphorylation Ras Protein Signal Transduction Regulation Of Cell Size Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Mammary Gland Epithelial Cell Proliferation Regulation Of GTPase Activity Positive Regulation Of MAPK Cascade ERK1 And ERK2 Cascade Cellular Response To Organic Substance
Pathways		RHO GTPases activate IQGAPs RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle
Drugs
Diseases
GWAS		Adult body size ( 32376654) Creatine kinase levels ( 29403010)
Interacting Genes		2 interacting genes: CALM2 CCDC198
Entrez ID		128239
HPRD ID		11051
Ensembl ID		ENSG00000183856
Uniprot IDs		Q86VI3
PDB IDs		3ISU
Enriched GO Terms of Interacting Partners?
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