SWSAP1 and RAD51C

Number of citations of the paper that reports this interaction (PubMedID 21965664)
37

Data Source:
BioGRID (affinity chromatography technology, pull down)

		SWSAP1	RAD51C
Description		SWIM-type zinc finger 7 associated protein 1	RAD51 paralog C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Shu Complex	Nucleus Nucleoplasm Replication Fork Cytoplasm Mitochondrion Cytosol Cell Junction Rad51B-Rad51C-Rad51D-XRCC2 Complex Rad51C-XRCC3 Complex Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Single-stranded DNA Binding Protein Binding ATP Hydrolysis Activity	Four-way Junction DNA Binding DNA Binding Protein Binding ATP Binding ATP-dependent Activity, Acting On DNA Crossover Junction Endodeoxyribonuclease Activity
	Biological Process	Double-strand Break Repair Via Homologous Recombination Protein Stabilization	Meiotic DNA Recombinase Assembly Telomere Maintenance Via Recombination Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Recombination Sister Chromatid Cohesion Female Meiosis Sister Chromatid Cohesion Reciprocal Meiotic Recombination Male Meiosis I Spermatogenesis Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Pathways			HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange Presynaptic phase of homologous DNA pairing and strand exchange Meiotic recombination Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Cognitive function ( 25644384) Primary tooth development (time to first tooth eruption) ( 23704328) Testicular germ cell tumor ( 23666239 23666240)
Interacting Genes		9 interacting genes: A2M EPM2AIP1 RAD51 RAD51B RAD51C RAD51D SPG21 XRCC3 ZSWIM7	9 interacting genes: APP GATA3 PALB2 RAD51 RAD51B RAD51D SPG21 SWSAP1 XRCC3
Entrez ID		126074	5889
HPRD ID		08179	04143
Ensembl ID		ENSG00000173928	ENSG00000108384
Uniprot IDs		Q6NVH7	O43502
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?