MBD3L2 and RBBP7

Number of citations of the paper that reports this interaction (PubMedID 15701600)
15

Data Source:
BioGRID (pull down)

		MBD3L2	RBBP7
Description		methyl-CpG binding domain protein 3 like 2	RB binding protein 7, chromatin remodeling factor
Image		No pdb structure
GO Annotations	Cellular Component		Histone Deacetylase Complex Nucleus Nucleoplasm Cytosol NuRD Complex ESC/E(Z) Complex
	Molecular Function	Protein Binding	RNA Binding Protein Binding Histone Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II DNA Replication Chromatin Organization Negative Regulation Of Cell Growth Response To Steroid Hormone Cellular Heat Acclimation
Pathways			PRC2 methylates histones and DNA Oxidative Stress Induced Senescence HDACs deacetylate histones PKMTs methylate histone lysines HATs acetylate histones RMTs methylate histone arginines ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Activation of anterior HOX genes in hindbrain development during early embryogenesis Deposition of new CENPA-containing nucleosomes at the centromere Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription Neddylation Transcriptional Regulation by E2F6 HCMV Early Events Potential therapeutics for SARS Defective pyroptosis
Drugs
Diseases
GWAS			Refractive error ( 32231278)
Interacting Genes		20 interacting genes: CCDC136 CHD4 GOLGA6L9 GPRASP2 HDAC1 HDAC2 KRT27 KRT34 KRTAP6-3 MBD2 MBD3 MDFI MTA1 MTA2 POLD3 RBBP4 RBBP7 RUNDC3A SBK3 TRIML2	35 interacting genes: APPL1 APPL2 BCL11A BCL11B BRCA1 BRMS1 BRMS1L BUB3 CREBBP CYTOR DHX30 ERCC6 ESR1 FOXK2 H3-4 H3C1 HDAC1 HDAC2 HUWE1 ING1 MBD3 MBD3L2 MTA2 NR2E3 OGT PRKAA2 RB1 RBBP4 RBP1 SALL2 SAP30 SIN3A SUMO2 SUV39H1 TWIST1
Entrez ID		125997	5931
HPRD ID		12139	04231
Ensembl ID		ENSG00000230522	ENSG00000102054
Uniprot IDs		Q8NHZ7	Q16576 Q6FHQ0
PDB IDs			3CFS 3CFV
Enriched GO Terms of Interacting Partners?
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