RBBP7

Description		RB binding protein 7, chromatin remodeling factor
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GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleus Nucleoplasm Cytosol NuRD Complex ESC/E(Z) Complex
	Molecular Function	RNA Binding Protein Binding Histone Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Replication Chromatin Organization Negative Regulation Of Cell Growth Response To Steroid Hormone Cellular Heat Acclimation
Pathways		PRC2 methylates histones and DNA Oxidative Stress Induced Senescence HDACs deacetylate histones PKMTs methylate histone lysines HATs acetylate histones RMTs methylate histone arginines ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Activation of anterior HOX genes in hindbrain development during early embryogenesis Deposition of new CENPA-containing nucleosomes at the centromere Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription Neddylation Transcriptional Regulation by E2F6 HCMV Early Events Potential therapeutics for SARS Defective pyroptosis
Drugs
Diseases
GWAS		Refractive error ( 32231278)
Interacting Genes		35 interacting genes: APPL1 APPL2 BCL11A BCL11B BRCA1 BRMS1 BRMS1L BUB3 CREBBP CYTOR DHX30 ERCC6 ESR1 FOXK2 H3-4 H3C1 HDAC1 HDAC2 HUWE1 ING1 MBD3 MBD3L2 MTA2 NR2E3 OGT PRKAA2 RB1 RBBP4 RBP1 SALL2 SAP30 SIN3A SUMO2 SUV39H1 TWIST1
Entrez ID		5931
HPRD ID		04231
Ensembl ID		ENSG00000102054
Uniprot IDs		Q16576 Q6FHQ0
PDB IDs		3CFS 3CFV
Enriched GO Terms of Interacting Partners?
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