LMO7 and UBAC2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		LMO7	UBAC2
Description		LIM domain 7	UBA domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nuclear Envelope Cytoplasm Cytosol Focal Adhesion Cell Surface Apical Plasma Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Metal Ion Binding	Protein Binding
	Biological Process	Protein Ubiquitination Regulation Of Signaling Regulation Of Cell Adhesion Positive Regulation Of Transcription By RNA Polymerase II	Wnt Signaling Pathway Protein Localization To Endoplasmic Reticulum Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways		Neddylation Signaling by ALK fusions and activated point mutants Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Cutaneous melanoma or hair colour ( 32341527) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary open-angle) ( 33627673 29449654) Initial pursuit acceleration ( 29064472) Initial pursuit acceleration in psychotic disorders ( 29064472) Intraocular pressure ( 29617998 29785010 31959993 30054594) Mean corpuscular hemoglobin ( 32888494) Multiple system atrophy (pathologically confirmed) ( 27629089) Obsessive-compulsive disorder ( 30456828) Type 1 diabetes ( 21980299)	Asthma ( 31361310 31959851 30929738 32296059 31619474) Asthma (childhood onset) ( 31036433 30929738) Basal cell carcinoma ( 21700618) Behcet's disease ( 33393726) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Cuneus cortex volume ( 31530798) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Inflammatory bowel disease ( 28067908) Medication use (adrenergics, inhalants) ( 31015401) Metabolite levels ( 23823483) Neutrophil percentage of granulocytes ( 27863252) Psoriasis ( 28537254) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus ( 33536424) Tinnitus ( 33742053)
Interacting Genes		12 interacting genes: ABCA1 CALM1 EMD LRIG3 MDM2 PKM RHOU SRPK2 SUMO2 UBAC2 YWHAG YWHAQ	5 interacting genes: CALCOCO2 GET4 LMO7 MIR182 UBC
Entrez ID		4008	337867
HPRD ID		05078	11429
Ensembl ID		ENSG00000136153	ENSG00000134882
Uniprot IDs		A0A0A0MTE2 E9PMT2 F8J2B5 F8WD26 Q8WWI1	A0A024RE02 A8K2S7 Q8NBM4
PDB IDs		2EAQ
Enriched GO Terms of Interacting Partners?
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