CLU and MAPK9

  • Number of citations of the paper that reports this interaction (PubMedID 21988832)
  • 87
  • Data Source:
  • BioGRID (two hybrid)

CLU

MAPK9

Description clusterin mitogen-activated protein kinase 9
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease ( 19734902 19734903 21627779 31473137)
  • Alzheimer's disease (late onset) ( 21460841 30617256 24162737 28714976)
  • Alzheimer's disease in APOE e4+ carriers ( 25778476)
  • Alzheimer's disease in APOE e4- carriers ( 25778476)
  • Alzheimer's disease or family history of Alzheimer's disease ( 33589840 30617256)
  • Alzheimer's disease or fasting insulin levels (pleiotropy) ( 30805717)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Family history of Alzheimer's disease ( 30617256)
  • Lung adenocarcinoma ( 28604730)
  • Lung cancer in ever smokers ( 28604730)
  • Panic disorder ( 19165232)
  • Refractive error ( 32231278)
  • Schizophrenia ( 25056061 29483656)
  • Smoking behaviour (cigarettes smoked per day) ( 31089300)
  • Smoking initiation ( 33082346)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes 59 interacting genes: ADGRF4 APP BAG6 C7 C8B C9 CBR3 CBY1 CD209 CLUAP1 CYP2E1 DISC1 DLG4 DUSP13 ELN EPPIN FOS GEMIN7 GRB2 HSPD1 IL24 KATNA1 KEAP1 KLF11 KNSTRN KRT12 LEP LEPR LIG4 LRP1 LRP2 LRP8 LYZ MAPK9 MDM2 MMP25 MSRB1 NAT2 PAXIP1 PLXNA4 POLR1C PON1 PRNP RBBP8 RPL23 SHANK3 SRPK2 SYVN1 TGFBR1 TGFBR2 TNIK TREM2 TSC22D4 TTR UBC VHL VLDLR XRCC6 ZWINT 113 interacting genes: ACP5 AKT1 ARRB1 ARRB2 ATF2 ATF7 BCL2L1 BCL2L11 BNIP5 C1orf105 C1orf94 CASP3 CBLL2 CCDC33 CDC16 CDC25B CDC25C CEP126 CEP44 CLU CTBP1 CTNNB1 CYHR1 DCX DTX3 DUSP10 DUSP16 DUSP19 DUSP4 EEF2K EFHC2 EGFR ELK1 ELK3 ENKD1 FBXO7 GFAP GOLGA6A GRB2 GSC2 H3-3A HDAC9 HSF1 IHO1 IRS1 ITGB3BP JDP2 JUN JUNB JUND KLHL8 KPNA3 L3MBTL3 LHX3 LMAN2 LNX1 LNX2 LZTS1 MACF1 MAP2K4 MAP2K7 MAP3K1 MAP3K10 MAPK8IP1 MAPK8IP2 MAPK8IP3 MAPKAPK5 MAPKBP1 MAPT MCRS1 MED12L MEOX1 MLIP NCF1 NCSTN NFATC3 NFATC4 NHSL2 PAX5 PBX4 PICK1 POU6F2 PPARG PRKD1 PSEN1 RASL10B RB1 RPS6KB1 RSPO4 SAXO1 SDCBP SF3B4 SH3BP5 SHMT1 SLIT3 SMAD2 SMAD3 SMCO3 SSU72 TCP10L TEX11 TOB1 TP53 TRAF2 TUSC2 WDR62 XPNPEP1 XPO7 ZBTB25 ZC2HC1C ZNF138 ZNF559 ZNHIT1
Entrez ID 1191 5601
HPRD ID 01706 04206
Ensembl ID ENSG00000120885 ENSG00000050748
Uniprot IDs P10909 D7R525 D7R526 P45984
PDB IDs 3E7O 3NPC 7CML
Enriched GO Terms of Interacting Partners?
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