EXOSC6 and MRPS18B

Number of citations of the paper that reports this interaction (PubMedID 15231747)
57

Data Source:
BioGRID (two hybrid)

		EXOSC6	MRPS18B
Description		exosome component 6	mitochondrial ribosomal protein S18B
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GO Annotations	Cellular Component	Nuclear Exosome (RNase Complex) Cytoplasmic Exosome (RNase Complex) Exosome (RNase Complex) Nucleoplasm Nucleolus Cytosol	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Small Ribosomal Subunit Cell Junction
	Molecular Function	RNA Binding Exoribonuclease Activity	Structural Constituent Of Ribosome Protein Binding
	Biological Process	RRNA Processing RRNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic, 3'-5' U4 SnRNA 3'-end Processing DNA Deamination Isotype Switching Positive Regulation Of Isotype Switching Nuclear MRNA Surveillance Polyadenylation-dependent SnoRNA 3'-end Processing	Translation Mitochondrial Translation
Pathways		ATF4 activates genes in response to endoplasmic reticulum stress mRNA decay by 3' to 5' exoribonuclease Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA KSRP (KHSRP) binds and destabilizes mRNA Major pathway of rRNA processing in the nucleolus and cytosol	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Malaria ( 31844061)	Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Neuroblastoma (pediatric) ( 32599975) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		34 interacting genes: C1QBP CHPF DCP1B DIS3 DNAJC30 EIF3I ESRRA EXOSC10 EXOSC2 EXOSC4 EXOSC5 EXOSC7 EXOSC8 EXOSC9 GSE1 LSM1 LSM7 LSM8 MAN2C1 MIF4GD MOCS3 MRPL4 MRPS18B MTREX NDUFA13 NUDT21 PALS2 PSMB1 RAB3GAP2 SRSF3 TUFM UPF2 XRN1 ZFP36	21 interacting genes: BMP10 CD81 CLEC1A ERCC6 EWSR1 EXOSC6 IGFBP5 LAT LRP10 MIP PHB2 RB1 SEC22B SLC35A1 SYS1 TMED8 TMEM120B TMEM128 TNFRSF10C TRARG1 ZFPL1
Entrez ID		118460	28973
HPRD ID		12107	14781
Ensembl ID		ENSG00000223496	ENSG00000204568
Uniprot IDs		Q5RKV6	B0S7P4 Q9Y676
PDB IDs		2NN6 6D6Q 6D6R 6H25	3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K
Enriched GO Terms of Interacting Partners?
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