SYNPO and NDST1

		SYNPO	NDST1
Description		synaptopodin	N-deacetylase and N-sulfotransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Cytosol Bicellular Tight Junction Postsynaptic Density Actin Cytoskeleton Z Disc Dendritic Spine Perikaryon Spine Apparatus	Golgi Membrane Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Actin Binding Protein Binding	Protein Binding [heparan Sulfate]-glucosamine N-sulfotransferase Activity Deacetylase Activity N-acetylglucosamine Deacetylase Activity Heparan Sulfate N-deacetylase Activity
	Biological Process	Positive Regulation Of Actin Filament Bundle Assembly Modification Of Dendritic Spine Spine Apparatus Assembly	Cardiac Septum Development Glycosaminoglycan Biosynthetic Process Protein Sulfation Inflammatory Response Respiratory Gaseous Exchange By Respiratory System Cell Population Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Heparan Sulfate Proteoglycan Biosynthetic Process, Polysaccharide Chain Biosynthetic Process Heparin Biosynthetic Process Forebrain Development Midbrain Development Aorta Development Positive Regulation Of MAPK Cascade Positive Regulation Of Smoothened Signaling Pathway Embryonic Neurocranium Morphogenesis Embryonic Viscerocranium Morphogenesis Coronary Vasculature Development
Pathways			HS-GAG biosynthesis
Drugs			Adenosine 3',5'-diphosphate
Diseases
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Medication use (anti-inflammatory and antirheumatic products, non-steroids) ( 31015401)	Blood protein levels ( 30072576) Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Neutrophil count ( 32888494)
Interacting Genes		11 interacting genes: CDC5L G3BP1 MAGI1 NCK1 NCK2 NDST1 NONO NUFIP2 SGF29 YWHAG YWHAZ	7 interacting genes: ABLIM3 ADAM18 CAMK2A HMGXB3 ITGA11 ST6GALNAC1 SYNPO
Entrez ID		11346	3340
HPRD ID		12179	02912
Ensembl ID		ENSG00000171992	ENSG00000070614
Uniprot IDs		Q8N3V7	A8K8T3 B7Z1Q0 E7EVJ3 P52848
PDB IDs			1NST
Enriched GO Terms of Interacting Partners?
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