SLC12A7 and SLC35C2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLC12A7	SLC35C2
Description		solute carrier family 12 member 7	solute carrier family 35 member C2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Protein-containing Complex Synapse	Nucleoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Integral Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Ammonium Transmembrane Transporter Activity Potassium:chloride Symporter Activity Protein Kinase Binding	Antiporter Activity
	Biological Process	Ion Transport Cell Volume Homeostasis Chemical Synaptic Transmission Chloride Ion Homeostasis Potassium Ion Homeostasis Ammonium Import Across Plasma Membrane Chloride Transmembrane Transport Potassium Ion Import Across Plasma Membrane	Negative Regulation Of Gene Expression UDP-glucose Transmembrane Transport Protein O-linked Fucosylation Positive Regulation Of Notch Signaling Pathway
Pathways		Cation-coupled Chloride cotransporters
Drugs		Potassium chloride
Diseases
GWAS		Granulocyte count ( 27863252) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte percentage of red cells ( 32888494) JT interval ( 29874175) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 29403010 32888494 20139978 27863252) Mean corpuscular volume ( 32888494 27863252) Mean platelet volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Pancreatic cancer ( 25086665) Platelet count ( 32888494) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494) PR interval ( 32439900) Red blood cell count ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte fraction of red cells ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Weight ( 28552196) White blood cell count ( 32888494)
Interacting Genes		14 interacting genes: GJB1 GPR61 MS4A13 OPRD1 OTP SERINC2 SLC10A1 SLC10A6 SLC35C2 TMBIM6 TMEM147 TMEM237 TMEM54 YIPF6	92 interacting genes: ACSL5 ADIPOQ AGPAT3 AGPAT4 APOD ARL6IP1 ASGR1 ATP13A1 BCL2L2 BMP10 C14orf180 C2 C4orf3 CCDC167 CLDN19 CMTM5 CNIH1 COL4A5 CREB3 CREB3L1 CYB561 CYBC1 DNAJC30 EFNA5 EMP3 FAM3C FDFT1 FFAR2 FXYD3 FXYD6 FXYD6-FXYD2 GIMAP5 GOLT1A GPR152 ITGAM LAT LEPROTL1 LHFPL5 LPAR3 MAL MAL2 MALL MS4A1 NRM ORMDL1 ORMDL3 PDCD1LG2 PEX16 PLN PLP2 PNLIPRP1 PRB1 RUSF1 SACM1L SEC22A SEC22B SELENOK SERP1 SLC10A6 SLC12A5 SLC12A7 SLC30A3 SLC35F1 SLC66A1 SMCO4 SSMEM1 STRIT1 STX3 SYNDIG1 SYS1 TAP1 THBD TMEM107 TMEM14B TMEM239 TMEM31 TMEM50B TMEM65 TMEM86A TPRG1 TSNARE1 TSPAN2 TSPAN33 TVP23B UNC93B1 UPK1B VAPB VEGFA VTI1B YIF1A YIPF4 YIPF6
Entrez ID		10723	51006
HPRD ID		09221	15371
Ensembl ID		ENSG00000113504	ENSG00000080189
Uniprot IDs		Q9Y666	B7Z6R4 Q9NQQ7
PDB IDs		7D99
Enriched GO Terms of Interacting Partners?
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