GPN1 and RPAP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		GPN1	RPAP2
Description		GPN-loop GTPase 1	RNA polymerase II associated protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Cytosol	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol RNA Polymerase II, Holoenzyme
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Protein Binding RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity RNA Polymerase Core Enzyme Binding Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process		SnRNA Transcription Dephosphorylation Of RNA Polymerase II C-terminal Domain
Pathways			RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Fasting blood glucose adjusted for BMI ( 25625282) Nonalcoholic fatty liver disease ( 29385134) Oral cavity cancer ( 27749845) Periodontitis (CDC/AAP) ( 24024966) Schizophrenia ( 26198764)	Granulocyte percentage of myeloid white cells ( 27863252) Lymphocyte counts ( 32888494) Monocyte count ( 27863252) Multiple sclerosis and C-reactive protein levels (pleiotropy) ( 26920376) Neutrophil percentage of white cells ( 32888494 27863252) Type 1 diabetes ( 34127860)
Interacting Genes		7 interacting genes: CSNK2A1 GPN2 MBD2 RAB10 RPAP2 XPA ZBED1	5 interacting genes: GPN1 ITCH NEDD4 PIH1D1 PLEKHF2
Entrez ID		11321	79871
HPRD ID		10308	07814
Ensembl ID		ENSG00000198522	ENSG00000122484
Uniprot IDs		Q53RZ9 Q9HCN4	Q8IXW5
PDB IDs
Enriched GO Terms of Interacting Partners?
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