GPN1 and XPA

Number of citations of the paper that reports this interaction (PubMedID 11058119)
26

Data Source:
HPRD (two hybrid)

		GPN1	XPA
Description		GPN-loop GTPase 1	XPA, DNA damage recognition and repair factor
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Cytosol	Nucleotide-excision Repair Factor 1 Complex Nucleus Nucleoplasm Cytoplasm Intercellular Bridge
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Damaged DNA Binding Protein Binding Protein Domain Specific Binding Protein Homodimerization Activity Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process		Nucleotide-excision Repair, DNA Damage Recognition DNA Repair Base-excision Repair UV Protection Response To Auditory Stimulus Nucleotide-excision Repair, DNA Incision Protein Localization To Nucleus UV-damage Excision Repair Nucleotide-excision Repair Involved In Interstrand Cross-link Repair
Pathways			Formation of Incision Complex in GG-NER Dual Incision in GG-NER Formation of TC-NER Pre-Incision Complex Dual incision in TC-NER
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Fasting blood glucose adjusted for BMI ( 25625282) Nonalcoholic fatty liver disease ( 29385134) Oral cavity cancer ( 27749845) Periodontitis (CDC/AAP) ( 24024966) Schizophrenia ( 26198764)	Hypothyroidism ( 27182965) Obesity-related traits ( 23251661) Serum thyroid-stimulating hormone levels ( 24852370) Thyroid cancer (Papillary, radiation-related) ( 20350937)
Interacting Genes		7 interacting genes: CSNK2A1 GPN2 MBD2 RAB10 RPAP2 XPA ZBED1	52 interacting genes: AP2M1 ARID3A ATM ATR AURKA BMPR1A BUB1 DDB1 DDB2 DLC1 DVL3 ERCC1 ERCC4 ERCC6 FBXW7 GPN1 GTF2E2 GTF2H1 HERC2 MEOX2 MLH1 MLH3 MSH2 MSH3 MUTYH NDEL1 NRAS PCNA PDGFRL PICK1 PMS2 POLR1C PRDM16 PRKDC PSMB1 RASSF1 RB1 RHOU RPA1 RPA2 RPA4 SKIL SMAD2 SNPH SRC STK11 TBC1D7 TRIM27 VPS26C XAB2 XPC ZNF655
Entrez ID		11321	7507
HPRD ID		10308	02045
Ensembl ID		ENSG00000198522	ENSG00000136936
Uniprot IDs		Q53RZ9 Q9HCN4	P23025
PDB IDs			1D4U 1XPA 2JNW 6J44 6LAE 6RO4
Enriched GO Terms of Interacting Partners?
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