NRM and RHBDD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NRM	RHBDD2
Description		nurim	rhomboid domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Inner Membrane Membrane Integral Component Of Membrane Nuclear Membrane	Golgi Membrane Hrd1p Ubiquitin Ligase ERAD-L Complex Nucleoplasm Golgi Apparatus Integral Component Of Endoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Molecular_function Protein Binding	Serine-type Endopeptidase Activity Misfolded Protein Binding Ubiquitin-specific Protease Binding
	Biological Process	Biological_process	Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response
Pathways
Drugs
Diseases
GWAS		Alcohol dependence symptom count ( 27151647) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Height ( 31217584) Itch intensity from mosquito bite ( 28199695) Number of sexual partners ( 30643258)	Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		50 interacting genes: AGR3 ANK1 AQP6 ARL13B ATP6V0B BIK CLRN1 CNR2 CPLX4 CREB3L1 CYB5R3 CYBC1 ERGIC3 ERP29 FAM209A FCER1G FFAR2 FRMD3 GOLT1A GORAB GPR151 GPR42 GPX8 HDAC11 HHLA2 HSD17B13 KIR2DL3 MFF MGST3 MRM1 OPN1LW PARP15 PEX12 RETREG3 RHBDD2 RMDN3 RNASEH1 SAR1A SLC10A2 SLC10A6 SLC18A1 SLC30A2 SLC35C2 SPAG4 SSMEM1 STX1A SUN2 TMEM52B TMX2 TRIM59	58 interacting genes: ABHD16A ACSF2 ADORA2A BCL2L1 BCL2L2 CCR9 CHRM4 CIAO2A CIDEB COL8A1 COMT DIABLO DRD2 DYNC1H1 ERBB2 FKBP8 FMO4 GAL3ST3 GCSH GDF5-AS1 H2BC3 H4C7 IFI27L1 IL32 LETMD1 LIG4 MAOB MFSD14C MICOS13 MIEF2 MLX MMRN2 MPC2 MRM1 MRPL35 MTERF3 MYG1 NAALAD2 NCBP2AS2 NFU1 NRM PBX3 PTAFR ROMO1 RSAD2 SCGB3A1 SDHD SLC25A2 SLC25A3 SNPH SYT16 TEX44 THBD TIMM17B TPRG1 TSR1 TUFM USP30
Entrez ID		11270	57414
HPRD ID		10120	11492
Ensembl ID		ENSG00000137404	ENSG00000005486
Uniprot IDs		A0A1U9X845 B3KQU6 Q8IXM6	Q6NTF9
PDB IDs
Enriched GO Terms of Interacting Partners?
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