NRM and TRIM59

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		NRM	TRIM59
Description		nurim	tripartite motif containing 59
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Inner Membrane Membrane Integral Component Of Membrane Nuclear Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Intraciliary Transport Particle B
	Molecular Function	Molecular_function Protein Binding	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Biological_process	Protein Ubiquitination Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell
Pathways
Drugs
Diseases
GWAS		Alcohol dependence symptom count ( 27151647) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Height ( 31217584) Itch intensity from mosquito bite ( 28199695) Number of sexual partners ( 30643258)	Alanine aminotransferase levels ( 33547301) Alcohol use disorder (total score) ( 30336701) Aspartate aminotransferase levels ( 33547301) Bipolar disorder ( 31043756) Eosinophil percentage of white cells ( 32888494) Intrinsic epigenetic age acceleration ( 29374233) Malaria ( 31844061) Pulse pressure ( 30578418) Systolic blood pressure ( 30578418)
Interacting Genes		50 interacting genes: AGR3 ANK1 AQP6 ARL13B ATP6V0B BIK CLRN1 CNR2 CPLX4 CREB3L1 CYB5R3 CYBC1 ERGIC3 ERP29 FAM209A FCER1G FFAR2 FRMD3 GOLT1A GORAB GPR151 GPR42 GPX8 HDAC11 HHLA2 HSD17B13 KIR2DL3 MFF MGST3 MRM1 OPN1LW PARP15 PEX12 RETREG3 RHBDD2 RMDN3 RNASEH1 SAR1A SLC10A2 SLC10A6 SLC18A1 SLC30A2 SLC35C2 SPAG4 SSMEM1 STX1A SUN2 TMEM52B TMX2 TRIM59	28 interacting genes: ANKRD33 BLZF1 CCDC33 CDK5 CLDN4 ECSIT EIF2B1 ESR1 ESR2 KRTAP13-3 MACROH2A1 MEI4 MRPL12 NECAB2 NRM OTOL1 PIN1 PLLP PPM1L RASSF3 RHOU SEC22A SNAP47 UBE2J2 UBE2W VTI1B ZDHHC21 ZDHHC22
Entrez ID		11270	286827
HPRD ID		10120	15568
Ensembl ID		ENSG00000137404	ENSG00000213186
Uniprot IDs		A0A1U9X845 B3KQU6 Q8IXM6	Q8IWR1
PDB IDs
Enriched GO Terms of Interacting Partners?
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