PRRT2 and TMEM219

		PRRT2	TMEM219
Description		proline rich transmembrane protein 2	transmembrane protein 219
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Synaptic Vesicle Membrane Synaptic Vesicle Membrane Vesicle Presynaptic Membrane Dendritic Spine Axon Terminus Presynapse Postsynaptic Density Membrane Glutamatergic Synapse Integral Component Of Presynaptic Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Syntaxin-1 Binding SH3 Domain Binding	Protein Binding
	Biological Process	Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Negative Regulation Of SNARE Complex Assembly Neuromuscular Process Controlling Posture Calcium-dependent Activation Of Synaptic Vesicle Fusion Negative Regulation Of Short-term Synaptic Potentiation	Apoptotic Process
Pathways			TP53 Regulates Transcription of Death Receptors and Ligands
Drugs
Diseases
GWAS			Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety/tension (special factor of neuroticism) ( 30867560) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Dentures ( 31235808) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Schizophrenia ( 28991256 25056061 29483656) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		13 interacting genes: AQP6 CFAP119 F2RL1 GPRC5D KAT8 MFSD14B ORAI3 SLC10A6 SMIM5 SNAP25 TLCD4 TMEM219 ZNF689	9 interacting genes: GSG1L KRBOX5 PRRT2 PRSS36 SGF29 STX1B ZNF688 ZNF689 ZNF785
Entrez ID		112476	124446
HPRD ID		13995	18546
Ensembl ID		ENSG00000167371	ENSG00000149932
Uniprot IDs		Q7Z6L0	A0A024R618 Q86XT9
PDB IDs
Enriched GO Terms of Interacting Partners?
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