ZHX1 and MPHOSPH6

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		ZHX1	MPHOSPH6
Description		zinc fingers and homeoboxes 1	M-phase phosphoprotein 6
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Exosome (RNase Complex) Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding Protein Heterodimerization Activity	RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cell Differentiation Negative Regulation Of Transcription, DNA-templated	Maturation Of 5.8S RRNA
Pathways			Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Leukocyte telomere length ( 32109421 31171785) Lung adenocarcinoma ( 28604730) Nevus count or cutaneous melanoma ( 32341527) Obesity-related traits ( 23251661) Parkinson's disease motor subtype (tremor dominant vs postural instability/gait difficulty) ( 33987465) Seasonality and depression ( 30217971)
Interacting Genes		54 interacting genes: AKR1C3 AKT1 ATXN1 BARD1 BCL2L1 BHLHE40 BID CHD3 CREB1 CREBBP CSNK2A1 DDX39B DLST DYNLL1 EFNA2 ELL GADD45A GNG11 GSK3B HSPE1 IDH1 LAMA4 LYAR MPHOSPH6 NACA NFYA PAFAH1B3 PEX14 PIAS4 PIGC PNP PRPF40A PSMD11 SAT1 SERPINB9 SUMO1 SUMO2 TAL1 TALDO1 TARDBP TERF1 TNFRSF10C TOLLIP TP53 UBC UTP3 VIM WDR33 ZBED1 ZHX2 ZHX3 ZMYND11 ZNF33B ZYX	30 interacting genes: AATF APLP1 ARHGAP18 DNM2 DYNLRB1 EIF3G ERG28 EXOSC10 EXOSC3 EXOSC5 EXOSC7 EXOSC8 FTL GDF9 HSBP1 HSPB1 KNSTRN LRIF1 MTREX NUPR1 PARN RBM48 RPS20 SMARCA4 SNX9 THOP1 TLE1 TP53 UNC119 ZHX1
Entrez ID		11244	10200
HPRD ID		10379	16111
Ensembl ID		ENSG00000165156	ENSG00000135698
Uniprot IDs		A0A024R9F1 Q9UKY1	H3BNT4 Q99547
PDB IDs		2ECB 2GHF 2LY9 3NAR	6D6Q 6D6R 6H25
Enriched GO Terms of Interacting Partners?
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