EGLN3 and FOXJ2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		EGLN3	FOXJ2
Description		egl-9 family hypoxia inducible factor 3	forkhead box J2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Chromatin Fibrillar Center Nucleus Nucleoplasm
	Molecular Function	Protein Binding Ferrous Iron Binding 2-oxoglutarate-dependent Dioxygenase Activity L-ascorbic Acid Binding Peptidyl-proline Dioxygenase Activity Peptidyl-proline 4-dioxygenase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Response To Hypoxia Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To DNA Damage Stimulus Protein Hydroxylation Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Regulation Of Cell Population Proliferation Regulation Of Neuron Apoptotic Process Cellular Response To Hypoxia	Regulation Of Transcription By RNA Polymerase II Male Meiosis I Spermatogenesis Negative Regulation Of Angiogenesis Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Blood Vessel Endothelial Cell Differentiation Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Pathways		Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Drugs		Ascorbic acid Roxadustat
Diseases
GWAS		Alzheimer's disease (late onset) ( 30820047) Daytime sleep phenotypes ( 27126917) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Iron status biomarkers (ferritin levels) ( 33536631) Red blood cell count ( 32888494)	Granulocyte percentage of myeloid white cells ( 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494)
Interacting Genes		39 interacting genes: ABI2 ADRB2 ATF4 CTBP2 DUSP7 EFHC2 EPAS1 EPOR FAM168B FOXJ2 GSC2 HIF1A HIF3A IK IKBKG IKZF3 LDB2 LNX1 MAPK1 MAPK7 MDM2 NCAPH2 NTAQ1 OS9 PKM PLEKHA2 PRPF19 RBBP8NL SERTAD1 SIAH2 SRP54 SUMO1 SUMO2 SUMO3 TP53 TTC23L WDR83 ZC2HC1A ZNF655	3 interacting genes: APP CSTF2T EGLN3
Entrez ID		112399	55810
HPRD ID		06972	17014
Ensembl ID		ENSG00000129521	ENSG00000065970
Uniprot IDs		B3KVT0 F8W1G2 Q3T1B0 Q9H6Z9	Q9P0K8
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?