WWP1 and TFAP2A

  • Number of citations of the paper that reports this interaction (PubMedID 9169421)
  • 44
  • Data Source:
  • HPRD (in vitro)

WWP1

TFAP2A

Description WW domain containing E3 ubiquitin protein ligase 1 transcription factor AP-2 alpha
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Estimated glomerular filtration rate ( 31152163)
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Breast cancer in BRCA2 mutation carriers ( 23544012)
  • Glucose homeostasis traits ( 25524916)
  • Iron status biomarkers (ferritin levels) ( 28334935)
  • Metabolite levels ( 23823483)
  • Ovarian cancer ( 30557369)
  • Refractive error ( 32231278)
  • Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
  • Zinc levels ( 26025379)
Interacting Genes 58 interacting genes: ARRDC1 ARRDC2 ARRDC3 ASH2L ATN1 CLCN5 CPSF6 DAG1 DAZAP2 DIDO1 DVL2 EWSR1 FAM189A2 FBXL18 HSPB1 IKBKG IL2RG IL6R KLF2 KLF5 LAPTM5 LATS1 LNX1 LZTR1 MACROH2A2 MIR19A MIR19B1 NFE2 NOTCH1 PCBD1 PHF20L1 PRKAA2 PRRG4 PYGM RASA1 RNF11 RTN4 RUNX1 SCNN1A SFTPC SHANK3 SMAD3 SMAD5 STAT6 TFAP2A TGIF1 TP53BP2 TRAF4 UBC UBE2D1 UBE2D2 UBE2D3 UBE2L3 WASL WBP1 WBP2 YWHAQ ZNF638 38 interacting genes: APC CASP1 CASP3 CASP6 CITED2 CITED4 CLTC CSNK2A1 CSNK2B CTNNB1 DEK EP300 EPN1 EPN2 EPS15 GSTO2 HIP1 INCA1 KCTD15 LDLRAP1 MAGI1 MKRN3 MYC NFKB1 NPM1 PPARG PRKAA2 PRKD1 RB1 SRA1 SUMO4 SYT1 TP53 UBE2I VEGFA WWP1 WWP2 YBX1
Entrez ID 11059 7020
HPRD ID 03811 00128
Ensembl ID ENSG00000123124 ENSG00000137203
Uniprot IDs Q9H0M0 P05549
PDB IDs 1ND7 2OP7 5HPS 5HPT 6J1X 6J1Y
Enriched GO Terms of Interacting Partners?
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