PIM2 and FBH1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		PIM2	FBH1
Description		Pim-2 proto-oncogene, serine/threonine kinase	F-box DNA helicase 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Chromatin Nucleus SCF Ubiquitin Ligase Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity	DNA Helicase Activity Double-stranded DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding DNA Translocase Activity ATP Hydrolysis Activity 3'-5' DNA Helicase Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Apoptotic Process Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Population Proliferation Response To Virus Positive Regulation Of Autophagy Negative Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Transcription, DNA-templated Protein Autophosphorylation Protein Stabilization	Double-strand Break Repair Via Homologous Recombination Recombinational Repair DNA Catabolic Process, Endonucleolytic Positive Regulation Of Protein Phosphorylation Cellular Response To DNA Damage Stimulus Cell Death Protein Ubiquitination Replication Fork Processing DNA Duplex Unwinding Negative Regulation Of Chromatin Binding Replication Fork Protection Response To Intra-S DNA Damage Checkpoint Signaling Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Double-strand Break Repair Via Homologous Recombination
Pathways
Drugs
Diseases
GWAS
Interacting Genes		16 interacting genes: ATXN1 BAD CUTC DAPK1 FBH1 FBP1 FBXO7 GSK3B HNRNPH3 HSF1 IKBKG NDUFB8 RPL21 SOCS1 TRIM14 ZNF821	9 interacting genes: CUL1 ESR1 PIM2 RAD51 RBX1 RPL13A SKP1 UBC ZDHHC17
Entrez ID		11040	84893
HPRD ID		02244	06243
Ensembl ID		ENSG00000102096	ENSG00000134452
Uniprot IDs		A0A024QYW7 Q9P1W9	B3KV95 F6UZG9 Q2TAK1 Q8NFZ0
PDB IDs		2IWI 4X7Q
Enriched GO Terms of Interacting Partners?
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