PAPOLA and FIP1L1

Number of citations of the paper that reports this interaction (PubMedID 14749727)
105

Data Source:
BioGRID (pull down)

		PAPOLA	FIP1L1
Description		poly(A) polymerase alpha	factor interacting with PAPOLA and CPSF1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleoplasm Cytosol MRNA Cleavage And Polyadenylation Specificity Factor Complex
	Molecular Function	Magnesium Ion Binding RNA Binding Polynucleotide Adenylyltransferase Activity Protein Binding ATP Binding Manganese Ion Binding	RNA Binding Protein Binding
	Biological Process	MRNA Polyadenylation MRNA 3'-end Processing Regulation Of MRNA 3'-end Processing RNA Polyadenylation	MRNA Polyadenylation Pre-mRNA Cleavage Required For Polyadenylation
Pathways		mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs	Transport of Mature mRNA Derived from an Intronless Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs Signaling by cytosolic PDGFRA and PDGFRB fusion proteins
Drugs		Cordycepin Triphosphate 3-sulfino-L-alanine Triphosphoric acid
Diseases
GWAS		Carboplatin disposition in epthelial ovarian cancer ( 29367611) Copper levels ( 26025379) Metabolite levels ( 23823483) Number of stillbirths in continuous marriage ( 30188897) Triglyceride levels in HIV infection ( 33109212)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) DNA methylation (variation) ( 23725790) Lymphocyte counts ( 32888494) Red blood cell count ( 28453575) Serum VEGFR2 concentration ( 25411163) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		6 interacting genes: CPSF1 CPSF3 FIP1L1 SMAD2 SNRPA YWHAE	30 interacting genes: APP CPSF4 CSNK2A1 GOLGA2 HMGB1 LIG4 MIR128-2 MIR15B MIR16-2 MIR19A MIR19B1 MIR205 MIR221 MIR34A MIR34B MIR9-3 MIR92A1 MIR92A2 MIRLET7B MIRLET7G MIRLET7I NAA10 OGT PAPOLA PRMT2 PRMT6 SGTA SRPK2 WWOX ZMYND19
Entrez ID		10914	81608
HPRD ID		10407	09646
Ensembl ID		ENSG00000090060	ENSG00000145216
Uniprot IDs		A0A024R6J7 A0A024R6M3 A0A0C4DGK1 P51003	Q6UN15
PDB IDs			7K95
Enriched GO Terms of Interacting Partners?
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