PAPOLA and CPSF3

Number of citations of the paper that reports this interaction (PubMedID 8302877)
23

Data Source:
HPRD (in vitro)

		PAPOLA	CPSF3
Description		poly(A) polymerase alpha	cleavage and polyadenylation specific factor 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex
	Molecular Function	Magnesium Ion Binding RNA Binding Polynucleotide Adenylyltransferase Activity Protein Binding ATP Binding Manganese Ion Binding	RNA Binding Endoribonuclease Activity 5'-3' Exoribonuclease Activity Protein Binding 5'-3' Exonuclease Activity Metal Ion Binding
	Biological Process	MRNA Polyadenylation MRNA 3'-end Processing Regulation Of MRNA 3'-end Processing RNA Polyadenylation	MRNA Polyadenylation MRNA Cleavage MRNA 3'-end Processing By Stem-loop Binding And Cleavage RNA Phosphodiester Bond Hydrolysis, Endonucleolytic RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways		mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs	Transport of Mature mRNA Derived from an Intronless Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs		Cordycepin Triphosphate 3-sulfino-L-alanine Triphosphoric acid
Diseases
GWAS		Carboplatin disposition in epthelial ovarian cancer ( 29367611) Copper levels ( 26025379) Metabolite levels ( 23823483) Number of stillbirths in continuous marriage ( 30188897) Triglyceride levels in HIV infection ( 33109212)
Interacting Genes		6 interacting genes: CPSF1 CPSF3 FIP1L1 SMAD2 SNRPA YWHAE	9 interacting genes: CLP1 FAM107A HSPB1 MIR19A MIR19B1 MIR92A2 PAPOLA POLR2A YWHAG
Entrez ID		10914	51692
HPRD ID		10407	05825
Ensembl ID		ENSG00000090060	ENSG00000119203
Uniprot IDs		A0A024R6J7 A0A024R6M3 A0A0C4DGK1 P51003	G5E9W3 Q9UKF6
PDB IDs			2I7T 2I7V 6M8Q 6V4X
Enriched GO Terms of Interacting Partners?
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