BRD8 and EP400

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (affinity chromatography technology, two hybrid, affinity chromatography technology)

		BRD8	EP400
Description		bromodomain containing 8	E1A binding protein p400
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Swr1 Complex Nucleoplasm Mitochondrion NuA4 Histone Acetyltransferase Complex	Swr1 Complex Nucleoplasm Nuclear Speck NuA4 Histone Acetyltransferase Complex
	Molecular Function	Protein Binding Nuclear Receptor Coactivator Activity Thyroid Hormone Receptor Binding	DNA Binding Chromatin Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP-dependent Chromatin Remodeler Activity Protein Antigen Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Histone Acetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Thyroid Hormone Stimulus	Histone H4 Acetylation Histone H2A Acetylation
Pathways		HATs acetylate histones	Formation of Senescence-Associated Heterochromatin Foci (SAHF) DNA Damage/Telomere Stress Induced Senescence HATs acetylate histones
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Menarche (age at onset) ( 25231870)	Body mass index ( 26426971) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252 28957414)
Interacting Genes		14 interacting genes: AGTR1 CD276 EP400 FSD2 IL3 MCRS1 MIS18A MRGBP PIN1 PPARG RXRA THRB TRRAP WEE1	13 interacting genes: ALAS1 BRD8 KAT5 MNS1 MYC NTAQ1 POLR1C RAD51 SUMO2 TBC1D4 TRAF2 TRRAP ZGPAT
Entrez ID		10902	57634
HPRD ID		04166	09378
Ensembl ID		ENSG00000112983	ENSG00000183495
Uniprot IDs		B4DEG9 B4DMS9 B4DN43 Q9H0E9	Q96L91
PDB IDs
Enriched GO Terms of Interacting Partners?
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