EP400 and MNS1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		EP400	MNS1
Description		E1A binding protein p400	meiosis specific nuclear structural 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Swr1 Complex Nucleoplasm Nuclear Speck NuA4 Histone Acetyltransferase Complex	Nuclear Envelope Intermediate Filament Axoneme Motile Cilium Sperm Flagellum
	Molecular Function	DNA Binding Chromatin Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP-dependent Chromatin Remodeler Activity Protein Antigen Binding	Protein Binding Identical Protein Binding
	Biological Process	Histone H4 Acetylation Histone H2A Acetylation	Sperm Axoneme Assembly Cilium Organization Positive Regulation Of Cilium Assembly Meiotic Cell Cycle Left/right Axis Specification
Pathways		Formation of Senescence-Associated Heterochromatin Foci (SAHF) DNA Damage/Telomere Stress Induced Senescence HATs acetylate histones
Drugs
Diseases
GWAS		Body mass index ( 26426971) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252 28957414)	Body shape index ( 34021172) Chronic lymphocytic leukemia ( 26956414 23770605) Clozapine-induced agranulocytosis ( 25187353) Hematology traits ( 30576415) Red blood cell count ( 32888494) Relative hand skill in reading disability ( 24068947) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		13 interacting genes: ALAS1 BRD8 KAT5 MNS1 MYC NTAQ1 POLR1C RAD51 SUMO2 TBC1D4 TRAF2 TRRAP ZGPAT	24 interacting genes: CCND3 CDR2 CEP63 DISC1 EP400 EWSR1 FCHSD2 GIGYF1 IQCB1 KDM1A KIAA0753 KRT34 KRT75 PICK1 RSPH14 SNX32 STMN3 THOC7 TNNI1 TNNI2 TRIM54 TXLNB USHBP1 ZMYND12
Entrez ID		57634	55329
HPRD ID		09378	10967
Ensembl ID		ENSG00000183495	ENSG00000138587
Uniprot IDs		Q96L91	B3KQ70 Q8NEH6
PDB IDs
Enriched GO Terms of Interacting Partners?
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