NPFFR2 and NPFF

Number of citations of the paper that reports this interaction (PubMedID 10851242)
32

Data Source:
HPRD (in vivo)

		NPFFR2	NPFF
Description		neuropeptide FF receptor 2	neuropeptide FF-amide peptide precursor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Actin Cytoskeleton	Extracellular Region Extracellular Space Dendrite Perikaryon Axon Terminus Postsynapse
	Molecular Function	G Protein-coupled Receptor Activity Neuropeptide Receptor Activity Opioid Receptor Binding Peptide Binding	G Protein-coupled Receptor Binding Signaling Receptor Binding Neuropeptide Hormone Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Detection Of Abiotic Stimulus Regulation Of MAPK Cascade Regulation Of Adenylate Cyclase Activity Regulation Of CAMP-dependent Protein Kinase Activity	Neuropeptide Signaling Pathway Chemical Synaptic Transmission Excitatory Postsynaptic Potential
Pathways		Orexin and neuropeptides FF and QRFP bind to their respective receptors G alpha (q) signalling events	Orexin and neuropeptides FF and QRFP bind to their respective receptors G alpha (q) signalling events
Drugs
Diseases
GWAS			Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		6 interacting genes: FKBP7 HCRT NPFF NPY TMEM218 TRARG1	4 interacting genes: NPFFR1 NPFFR2 NPY ZDHHC17
Entrez ID		10886	8620
HPRD ID		16244	06869
Ensembl ID		ENSG00000056291	ENSG00000139574
Uniprot IDs		A0PJM9 Q9Y5X5	O15130
PDB IDs
Enriched GO Terms of Interacting Partners?
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