USP20 and APBA2

Number of citations of the paper that reports this interaction (PubMedID 19615732)
729

Data Source:
BioGRID (affinity chromatography technology, two hybrid, affinity chromatography technology)

		USP20	APBA2
Description		ubiquitin specific peptidase 20	amyloid beta precursor protein binding family A member 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Perinuclear Region Of Cytoplasm	Cytoplasm Plasma Membrane Synaptic Vesicle Dendritic Spine
	Molecular Function	G Protein-coupled Receptor Binding Cysteine-type Endopeptidase Activity Thiol-dependent Deubiquitinase Protein Binding Zinc Ion Binding	Amyloid-beta Binding Protein Binding Identical Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Endocytosis Regulation Of G Protein-coupled Receptor Signaling Pathway Protein Deubiquitination Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination	Chemical Synaptic Transmission Nervous System Development Protein Transport
Pathways		Ub-specific processing proteases	Neurexins and neuroligins
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Response to mTOR inhibitor (rapamycin) ( 24009623) SAPHO syndrome ( 33816493) Skin pigmentation (conditioned on rs1426654 and rs35397) ( 31315583) Temperament ( 22832960)
Interacting Genes		69 interacting genes: AGR2 ALAS1 APBA2 ARID5A ASCL1 ATP6V1G2 BEND5 BEND7 BHLHB9 BRPF1 C1QTNF2 CCNL2 CDK2AP1 CLSPN CTAG1A CTAG1B DIO2 ENKD1 EPAS1 FATE1 FTO GPRASP2 GTF2IRD1 HAND2 HIF1A HSF2BP IHO1 IRAK1BP1 ITGB3BP KLHL20 LMNA MAGEA11 MAPK6 MBD3L1 MCCD1 MDFI MEOX2 MRPL28 PBX4 PJA1 PLA2G2A PRKACA PRKCI RAD17 RSPO4 SAMD12 SPRY2 SRGAP2B STING1 TNNI1 TRIB3 TRIM23 TTC19 TTC23L ULK1 USP15 USP21 USP28 VAPA VAPB VAX1 VHL WASHC1 ZBTB10 ZFYVE26 ZNF343 ZNF408 ZNF620 ZXDB	15 interacting genes: APP ARF3 ARF4 CLSTN1 CLSTN3 LRP1 LRP2 LRP8 MAGEB6 MAPK6 NECAB3 NRXN1 RELA STXBP1 USP20
Entrez ID		10868	321
HPRD ID		07505	04090
Ensembl ID		ENSG00000136878	ENSG00000034053
Uniprot IDs		Q9Y2K6	Q59G28 Q99767
PDB IDs		6KCZ
Enriched GO Terms of Interacting Partners?
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