KHDRBS3 and RFC3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KHDRBS3	RFC3
Description		KH RNA binding domain containing, signal transduction associated 3	replication factor C subunit 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Protein-containing Complex	Nucleus Nucleoplasm DNA Replication Factor C Complex Ctf18 RFC-like Complex
	Molecular Function	RNA Binding MRNA Binding Protein Binding SH3 Domain Binding Protein Domain Specific Binding Identical Protein Binding	DNA Binding DNA Clamp Loader Activity Protein Binding ATP-dependent Activity, Acting On DNA Single-stranded DNA Helicase Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome	DNA Synthesis Involved In DNA Repair DNA Replication DNA-dependent DNA Replication DNA Strand Elongation Involved In DNA Replication DNA Repair DNA Duplex Unwinding Response To Organophosphorus Positive Regulation Of DNA-directed DNA Polymerase Activity
Pathways		PTK6 Regulates Proteins Involved in RNA Processing	Translesion synthesis by REV1 Recognition of DNA damage by PCNA-containing replication complex Translesion Synthesis by POLH Polymerase switching on the C-strand of the telomere Activation of ATR in response to replication stress PCNA-Dependent Long Patch Base Excision Repair Translesion synthesis by POLK Translesion synthesis by POLI Termination of translesion DNA synthesis HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Regulation of TP53 Activity through Phosphorylation Polymerase switching G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Chronotype ( 30696823) Colorectal cancer ( 34062886) Disease progression in age-related macular degeneration ( 29346644) Polycystic ovary syndrome ( 25574032) Squamous cell lung carcinoma ( 28604730) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Alzheimer's disease ( 20061627) Colorectal cancer or advanced adenoma ( 30510241) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Obesity-related traits ( 23251661)
Interacting Genes		57 interacting genes: AQP1 BAHD1 CACNA1A CCDC187 CCDC33 CNNM3 DMRT3 DOCK2 FBXO7 FUS FXR1 HBZ HNRNPC HNRNPK INPP5D KHDRBS1 KHDRBS2 LMNTD2 LNX1 MARK4 MYPOP NCOA5 NELFB NUDT18 OGT PCDHB14 PPP1R13B PRMT1 PRPF31 PRR3 PSMA1 PSMF1 PTBP2 RASAL3 RASD1 RBBP6 RBM3 RBM7 RBMX RBMY1A1 RFC3 RPH3AL SGSM2 SIAH1 SLIT3 SNRPC SNX18 SRSF9 TSGA10IP TYK2 U2AF2 YTHDC1 ZNF326 ZNF408 ZNF575 ZNF580 ZNF688	13 interacting genes: ANKRD40 ARFGAP1 CHTF8 INCA1 KHDRBS2 KHDRBS3 MESD PCNA PICK1 PTEN RAD17 RFC1 RFC4
Entrez ID		10656	5983
HPRD ID		10007	02676
Ensembl ID		ENSG00000131773	ENSG00000133119
Uniprot IDs		O75525	A0A024RDQ8 P40938
PDB IDs		5EL3 5ELR 5ELS 5ELT 5EMO	6VVO
Enriched GO Terms of Interacting Partners?
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