TXNIP and LUC7L3

Number of citations of the paper that reports this interaction (PubMedID 31669268)
4

Data Source:
BioGRID (two hybrid)

		TXNIP	LUC7L3
Description		thioredoxin interacting protein	LUC7 like 3 pre-mRNA splicing factor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrial Intermembrane Space Cytosol	Nucleus Nucleoplasm U1 SnRNP Nuclear Speck U2-type Prespliceosome
	Molecular Function	Enzyme Inhibitor Activity Protein Binding Ubiquitin Protein Ligase Binding	DNA Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Import Into Nucleus Cell Cycle Response To Xenobiotic Stimulus Response To Mechanical Stimulus Response To Glucose Protein Transport Keratinocyte Differentiation Response To Estradiol Response To Progesterone Regulation Of Cell Population Proliferation Response To Hydrogen Peroxide Positive Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Platelet-derived Growth Factor Receptor Signaling Pathway Response To Calcium Ion Negative Regulation Of Cell Division Cellular Response To Tumor Cell	MRNA Splice Site Selection RNA Splicing
Pathways		The NLRP3 inflammasome The NLRP3 inflammasome Regulation of FOXO transcriptional activity by acetylation Purinergic signaling in leishmaniasis infection Purinergic signaling in leishmaniasis infection Cytoprotection by HMOX1
Drugs
Diseases
GWAS			Mild to moderate chronic kidney disease ( 31178898)
Interacting Genes		28 interacting genes: CBX8 DDIT4 ECD EEF1A1 FHL1 GAPDH HDAC1 HDAC3 HSPB2 IDI1 INTS9 KPNA2 LUC7L3 MAPK1 NLGN3 PRKAA1 PTPN11 RUVBL2 SCEL SIVA1 SMURF2 TRAF6 TXN TXNRD1 UBR5 UXT ZBTB16 ZBTB32	11 interacting genes: CLK1 ITSN2 MLH1 OGT RNPS1 SRPK1 SRPK2 SRSF1 TLR10 TXNIP YWHAG
Entrez ID		10628	51747
HPRD ID		05964	16759
Ensembl ID		ENSG00000265972	ENSG00000108848
Uniprot IDs		Q9H3M7	A8K3C5 J3KPP4 O95232 Q86Y74
PDB IDs		4GEI 4GEJ 4GFX 4LL1 4LL4 4ROF 4ROJ 5CQ2 5DF6 5DWS 5DZD
Enriched GO Terms of Interacting Partners?
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