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TXNIP

Description thioredoxin interacting protein
Image
GO Annotations Cellular Component
  • Nucleus
  • Cytoplasm
  • Mitochondrial Intermembrane Space
  • Cytosol
Molecular Function
  • Enzyme Inhibitor Activity
  • Protein Binding
  • Ubiquitin Protein Ligase Binding
Biological Process
  • Negative Regulation Of Transcription By RNA Polymerase II
  • Protein Import Into Nucleus
  • Cell Cycle
  • Response To Xenobiotic Stimulus
  • Response To Mechanical Stimulus
  • Response To Glucose
  • Protein Transport
  • Keratinocyte Differentiation
  • Response To Estradiol
  • Response To Progesterone
  • Regulation Of Cell Population Proliferation
  • Response To Hydrogen Peroxide
  • Positive Regulation Of Apoptotic Process
  • Negative Regulation Of Catalytic Activity
  • Platelet-derived Growth Factor Receptor Signaling Pathway
  • Response To Calcium Ion
  • Negative Regulation Of Cell Division
  • Cellular Response To Tumor Cell
Pathways
  • The NLRP3 inflammasome
  • The NLRP3 inflammasome
  • Regulation of FOXO transcriptional activity by acetylation
  • Purinergic signaling in leishmaniasis infection
  • Purinergic signaling in leishmaniasis infection
  • Cytoprotection by HMOX1
Drugs
Diseases
GWAS
Interacting Genes 28 interacting genes: CBX8 DDIT4 ECD EEF1A1 FHL1 GAPDH HDAC1 HDAC3 HSPB2 IDI1 INTS9 KPNA2 LUC7L3 MAPK1 NLGN3 PRKAA1 PTPN11 RUVBL2 SCEL SIVA1 SMURF2 TRAF6 TXN TXNRD1 UBR5 UXT ZBTB16 ZBTB32
Entrez ID 10628
HPRD ID 05964
Ensembl ID ENSG00000265972
Uniprot IDs Q9H3M7
PDB IDs 4GEI 4GEJ 4GFX 4LL1 4LL4 4ROF 4ROJ 5CQ2 5DF6 5DWS 5DZD
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025