MYL12A and SUV39H2

Number of citations of the paper that reports this interaction (PubMedID 23455924)
46

Data Source:
BioGRID (two hybrid)

		MYL12A	SUV39H2
Description		myosin light chain 12A	SUV39H2 histone lysine methyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cytosol Myosin II Complex Z Disc Extracellular Exosome	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm
	Molecular Function	Calcium Ion Binding Protein Binding Glutamate Receptor Binding	Transcription Cis-regulatory Region Binding Protein Binding Zinc Ion Binding Histone-lysine N-methyltransferase Activity Histone Methyltransferase Activity (H3-K9 Specific) S-adenosyl-L-methionine Binding
	Biological Process	Regulation Of Cell Shape Platelet Aggregation Protein Localization To Plasma Membrane	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Assembly Or Disassembly Chromatin Remodeling Cell Cycle Cell Differentiation Histone Lysine Methylation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia
Pathways		EPHA-mediated growth cone collapse Sema4D induced cell migration and growth-cone collapse Smooth Muscle Contraction RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs Ephrin signaling Smooth Muscle Contraction	PKMTs methylate histone lysines
Drugs		4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACID
Diseases
GWAS		Night sleep phenotypes ( 27126917) QRS duration ( 27577874)	Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		5 interacting genes: CDKN2A GSK3A HSPB1 PTEN SUV39H2	41 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57
Entrez ID		10627	79723
HPRD ID		14735	07580
Ensembl ID		ENSG00000101608	ENSG00000152455
Uniprot IDs		J3QRS3 O14950 P19105	Q9H5I1
PDB IDs			2R3A 6P0R
Enriched GO Terms of Interacting Partners?
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