DCTN2 and RPGR

Number of citations of the paper that reports this interaction (PubMedID 16043481)
69

Data Source:
HPRD (in vivo)

		DCTN2	RPGR
Description		dynactin subunit 2	retinitis pigmentosa GTPase regulator
Image		No pdb structure
GO Annotations	Cellular Component	Kinetochore Cytoplasm Centrosome Cytosol Dynactin Complex Microtubule Membrane Dynein Complex Growth Cone Vesicle Extracellular Exosome	Photoreceptor Outer Segment Golgi Apparatus Centrosome Ciliary Basal Body Sperm Flagellum
	Molecular Function	Protein Binding Protein Kinase Binding Spectrin Binding Identical Protein Binding	RNA Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Mitotic Spindle Organization Mitotic Metaphase Plate Congression Melanosome Transport Protein Localization To Centrosome	Intracellular Protein Transport Visual Perception Intraciliary Transport Regulation Of Catalytic Activity Response To Stimulus Cilium Assembly
Pathways		MHC class II antigen presentation Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic AURKA Activation by TPX2
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)
Interacting Genes		39 interacting genes: ABI2 BICD1 BICD2 BLOC1S1 BLOC1S2 BLOC1S6 CALM1 CCDC172 CENPH CEP44 COG3 DISC1 EGFR FXR1 FXR2 GADD45A GADD45G GNAO1 GOLM1 GRB2 GSK3B HAUS1 HGS KIFC3 KPNA2 MAPK6 MAPRE3 MARCKSL1 OGT PAFAH1B1 RABGEF1 RINT1 RPGR SHANK3 SMARCD1 TSC1 TXLNB USHBP1 ZW10	19 interacting genes: ATP6AP2 DCTN1 DCTN2 HOMEZ IFT88 KIF3A KIFAP3 NPM1 NUDT12 PDE6D RPGRIP1 SLC25A10 SLC9A7 SMC1A SMC3 TSPAN7 TUBG1 USP9X YWHAE
Entrez ID		10540	6103
HPRD ID		09568	02425
Ensembl ID		ENSG00000175203	ENSG00000156313
Uniprot IDs		A0A384MDU9 A8K8J9 B3KTX4 Q13561 V9HW58	Q92834
PDB IDs			4JHN 4JHP 4QAM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?