UNC13B and RIMS1

  • Number of citations of the paper that reports this interaction (PubMedID 11797009)
  • 228
  • Data Source:
  • HPRD (two hybrid, in vivo, in vitro)

UNC13B

RIMS1

Description unc-13 homolog B regulating synaptic membrane exocytosis 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced) ( 24236485)
  • Adverse response to chemotherapy (amenorrhea) in breast cancer ( 31371054)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Bipolar disorder ( 33263727 31043756)
  • Chronotype ( 30696823)
  • Cognitive performance ( 20125193)
  • LDL levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429)
  • Lung cancer ( 28604730)
  • Lung cancer in never smokers ( 28604730)
  • Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
  • Refractive error ( 32231278)
  • Response to mTOR inhibitor (rapamycin) ( 24009623)
  • Rosacea symptom severity ( 29771307)
  • Schizophrenia ( 25056061 29483656 30285260)
  • Squamous cell lung carcinoma ( 28604730)
  • Total cholesterol levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder ( 33824429)
  • Triglyceride levels ( 32203549)
Interacting Genes 11 interacting genes: CLK1 DOC2A DOC2B PDCL2 RIMS1 RPH3AL SPTBN2 STX1A STX1B STX2 TOE1 17 interacting genes: CACNA1B CACNA1C CAMK2A COL9A1 ERC1 ERC2 RAB10 RAB26 RAB27A RAB37 RAB3A SNAP25 STX1A SYT1 UNC13B VAV1 YWHAH
Entrez ID 10497 22999
HPRD ID 05785 09435
Ensembl ID ENSG00000198722 ENSG00000079841
Uniprot IDs O14795 Q4LE73 B7Z7W2 B7Z9Z3 Q3ZCW0 Q86UR5
PDB IDs 2CSS
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?