ENOX2 and TRAF5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		ENOX2	TRAF5
Description		ecto-NOX disulfide-thiol exchanger 2	TNF receptor associated factor 5
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytosol Plasma Membrane External Side Of Plasma Membrane	Centrosome Cytosol Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex Plasma Membrane Signaling Receptor Complex
	Molecular Function	Nucleic Acid Binding Protein-disulfide Reductase Activity	Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Thioesterase Binding Identical Protein Binding
	Biological Process	Ultradian Rhythm Electron Transport Chain Regulation Of Growth	Apoptotic Process Signal Transduction Positive Regulation Of Cell Population Proliferation Signal Transduction Involved In Regulation Of Gene Expression Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of JNK Cascade MRNA Stabilization Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Protein K63-linked Ubiquitination Interleukin-17-mediated Signaling Pathway
Pathways
Drugs		Idronoxil
Diseases
GWAS		Hemoglobin ( 32888494)	Household income (MTAG) ( 31844048)
Interacting Genes		20 interacting genes: CDC37 CIB3 ENOX1 GORASP2 INTS4 LNX1 MAGEA11 MAGEA3 MLLT6 NDOR1 NTAQ1 RNF135 SNRPA SRPK2 STAMBPL1 TFIP11 TRAF5 TUBB4B VCL ZFP2	66 interacting genes: BEX3 CAPNS1 CCDC184 CD27 CD40 CDC37 CIB3 COG7 COMMD3 DGKH ENOX2 FAM9A FBXO28 GAS8 GOLGA2 GORASP2 HOMER1 HSD17B10 HSF2BP LMO4 LNX1 LTBR MAP3K14 MAP3K5 MDM2 MEOX2 NMI NTAQ1 NUMBL ODF2 PIAS2 PIBF1 PICK1 PSMA1 RAD23A RIPK1 RIPK2 RNF111 RNF4 SDCBP SEC13 SERPINB9 SUMO1 TBK1 TDP2 THAP1 THAP7 TNFRSF11A TNFRSF12A TNFRSF13B TNFRSF14 TNFRSF19 TNFRSF4 TNFRSF8 TRAF2 TRAF3 TRAF3IP2 TRAF6 TRIM27 TRIM37 TRIM8 UBC USP7 YPEL5 ZFAND6 ZNF655
Entrez ID		10495	7188
HPRD ID		02234	03834
Ensembl ID		ENSG00000165675	ENSG00000082512
Uniprot IDs		Q16206 Q32ND0	O00463
PDB IDs			7L3L
Enriched GO Terms of Interacting Partners?
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