MCRS1 and BRD8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MCRS1	BRD8
Description		microspherule protein 1	bromodomain containing 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Polysome Dendrite Ino80 Complex Perikaryon NSL Complex MLL1 Complex	Swr1 Complex Nucleoplasm Mitochondrion NuA4 Histone Acetyltransferase Complex
	Molecular Function	G-quadruplex RNA Binding Protein Binding Poly(U) RNA Binding Poly(G) Binding	Protein Binding Nuclear Receptor Coactivator Activity Thyroid Hormone Receptor Binding
	Biological Process	DNA Repair DNA Recombination Cellular Protein Modification Process Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Localization To Nucleolus	Cell Surface Receptor Signaling Pathway Histone Acetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Thyroid Hormone Stimulus
Pathways		HATs acetylate histones UCH proteinases DNA Damage Recognition in GG-NER	HATs acetylate histones
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Menarche (age at onset) ( 25231870)
Interacting Genes		128 interacting genes: AGGF1 AXIN2 BACH2 BEND3 BHLHA9 BHLHE40 BLM BRD8 BRMS1 BRMS1L C18orf25 C2CD6 C7orf57 C8orf34 CARD9 CAVIN2 CBY2 CCDC13 CCDC136 CCDC85B CCHCR1 CCNH CDCA7L CEP44 CEP70 CNTROB COIL CREB3L3 CSRNP1 CYSRT1 CYTIP DAXX DDN DRAP1 DVL2 EGR2 ERF EVI5 FAM9A FNDC8 FSD2 FXR1 FXR2 GAS7 GCC1 GEM GIGYF1 GOLGA2 GPBP1 HMBOX1 HOOK2 IKZF1 IKZF3 IKZF4 INO80E INSYN1 JAKMIP1 KANK2 KAT7 KDM1A KIAA1958 KRT35 KRTAP10-7 KRTAP2-3 KRTAP2-4 KXD1 LIG4 LSM6 LZTS1 MAGEA11 MAGEA6 MAPK9 MED4 MEOX1 MFAP1 MIER2 MIER3 NAA10 NAB2 NKAPD1 NOP2 OSBPL3 PBK PBX2 PCM1 PHC2 PIBF1 PINX1 PKNOX2 PPP1R13B PRMT5 PSTPIP1 PTEN RABEP1 RALYL RARA RETREG3 RIPPLY3 SH2B2 SHANK3 SNAPC5 SP4 SRRM4 SSMEM1 SUV39H1 TADA2B TBC1D1 TERT TFAP4 TLE5 TNIP1 TNNI1 TP63 TRIM37 TRIM41 TSPYL2 UPF3B USHBP1 WASHC3 WBP11 XIAP ZBTB22 ZCCHC10 ZCCHC12 ZNF23 ZNF639 ZNF8 ZRANB1	14 interacting genes: AGTR1 CD276 EP400 FSD2 IL3 MCRS1 MIS18A MRGBP PIN1 PPARG RXRA THRB TRRAP WEE1
Entrez ID		10445	10902
HPRD ID		11298	04166
Ensembl ID		ENSG00000187778	ENSG00000112983
Uniprot IDs		A0A024R134 Q96EZ8	B4DEG9 B4DMS9 B4DN43 Q9H0E9
PDB IDs
Enriched GO Terms of Interacting Partners?
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