C1D and SASH1

Number of citations of the paper that reports this interaction (PubMedID 30480076)
7

Data Source:
BioGRID (two hybrid)

		C1D	SASH1
Description		C1D nuclear receptor corepressor	SAM and SH3 domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Nucleus Nucleoplasm Nucleolus Cytoplasm Transcription Repressor Complex	Cytoplasm Protein-containing Complex
	Molecular Function	DNA Binding Transcription Corepressor Activity RNA Binding Protein Binding Nuclear Receptor Binding	G-protein Alpha-subunit Binding Protein Binding Protein C-terminus Binding Protein Kinase Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Molecular Adaptor Activity
	Biological Process	Maturation Of 5.8S RRNA Apoptotic Process Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated	Protein Polyubiquitination Positive Regulation Of Endothelial Cell Migration Regulation Of Epithelial Cell Migration Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of JUN Kinase Activity Positive Regulation Of Angiogenesis Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of P38MAPK Cascade Positive Regulation Of NIK/NF-kappaB Signaling Regulation Of Protein Autoubiquitination
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Familial lung adenocarcinoma ( 29924316) Male-pattern baldness ( 27182965) Obstetric antiphospholipid syndrome ( 28424481) PR interval ( 32439900) Restless legs syndrome ( 29029846) Schizophrenia x sex interaction ( 34099189) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)	Alzheimer's disease ( 20061627) Chronotype ( 30696823) Gait speed in old age ( 28077804) Hypothyroidism ( 27182965) Idiopathic dilated cardiomyopathy ( 29495422) Metabolite levels ( 23823483) Myocardial infarction ( 33532862) Night sleep phenotypes ( 27126917) Pneumococcal meningitis x streptococcus pneumoniae antigen allele interaction ( 31092817) Protein quantitative trait loci ( 18464913) Resting-state electroencephalogram vigilance ( 29703947) Rotator cuff tears ( 26350878) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 32769997) Type 2 diabetes nephropathy ( 21150874)
Interacting Genes		16 interacting genes: APP GSC2 IL23R MOGS NCOR1 NCOR2 NR1D1 PCBD2 PRKDC SASH1 SH3GLB1 SUOX THRA THRB TSNAX ZGPAT	26 interacting genes: AFF1 AKAP10 ARRB1 ASCC2 C1D CCNDBP1 CNKSR1 CRK CRKL CTNNA1 EPS8L2 EXOC8 IKBKB JADE2 JADE3 KHDRBS1 KIF3B PPP4R1 RBM12B SECISBP2L SKIL SNX1 SPG7 SYNE2 TNKS2 UTRN
Entrez ID		10438	23328
HPRD ID		07382	06408
Ensembl ID		ENSG00000197223	ENSG00000111961
Uniprot IDs		Q13901	O94885
PDB IDs			2DL0 2EBP
Enriched GO Terms of Interacting Partners?
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