SEC24B and SCAP

Number of citations of the paper that reports this interaction (PubMedID 19706601)
25

Data Source:
BioGRID (pull down)

		SEC24B	SCAP
Description		SEC24 homolog B, COPII coat complex component	SREBF chaperone
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GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane COPII Vesicle Coat Endoplasmic Reticulum Exit Site	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Protein-containing Complex
	Molecular Function	SNARE Binding Protein Binding Zinc Ion Binding	Protein Binding Sterol Binding Protein-containing Complex Binding Unfolded Protein Binding
	Biological Process	Neural Tube Closure Outflow Tract Morphogenesis Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cochlear Nucleus Development Aorta Morphogenesis Auditory Receptor Cell Stereocilium Organization Lung Lobe Morphogenesis Coronary Artery Morphogenesis Pulmonary Artery Morphogenesis COPII-coated Vesicle Cargo Loading Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Regulation Of Cargo Loading Into COPII-coated Vesicle	Response To Hypoxia Immune Response Aging Cholesterol Metabolic Process Response To Insulin SREBP Signaling Pathway Regulation Of Fatty Acid Biosynthetic Process Cellular Lipid Metabolic Process Negative Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Cholesterol Biosynthetic Process COPII-coated Vesicle Cargo Loading
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER Antigen Presentation: Folding, assembly and peptide loading of class I MHC	Regulation of cholesterol biosynthesis by SREBP (SREBF) Regulation of cholesterol biosynthesis by SREBP (SREBF)
Drugs
Diseases
GWAS		Late-onset Alzheimer's disease ( 27770636)	Refractive error ( 32231278) Triglyceride levels ( 32203549)
Interacting Genes		2 interacting genes: SCAP SEC23A	12 interacting genes: ATG16L1 DHX30 HIPK2 INSIG1 INSIG2 KLHL18 LAMC2 NDUFAF3 PGRMC1 SEC24B SREBF2 WDR6
Entrez ID		10427	22937
HPRD ID		06216	03300
Ensembl ID		ENSG00000138802	ENSG00000114650
Uniprot IDs		B4DTM6 O95487	B7Z6H0 Q12770
PDB IDs		3EH1	6M49
Enriched GO Terms of Interacting Partners?
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