SCAP and DHX30

		SCAP	DHX30
Description		SREBF chaperone	DExH-box helicase 30
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Protein-containing Complex	Intracellular Anatomical Structure Cytoplasm Mitochondrion Cytosol Ribonucleoprotein Granule Mitochondrial Nucleoid
	Molecular Function	Protein Binding Sterol Binding Protein-containing Complex Binding Unfolded Protein Binding	Chromatin Binding RNA Binding RNA Helicase Activity Double-stranded RNA Binding Protein Binding ATP Binding ATP Hydrolysis Activity
	Biological Process	Response To Hypoxia Immune Response Aging Cholesterol Metabolic Process Response To Insulin SREBP Signaling Pathway Regulation Of Fatty Acid Biosynthetic Process Cellular Lipid Metabolic Process Negative Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Cholesterol Biosynthetic Process COPII-coated Vesicle Cargo Loading	Central Nervous System Development Mitochondrial Large Ribosomal Subunit Assembly
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) Regulation of cholesterol biosynthesis by SREBP (SREBF)
Drugs
Diseases
GWAS		Refractive error ( 32231278) Triglyceride levels ( 32203549)
Interacting Genes		12 interacting genes: ATG16L1 DHX30 HIPK2 INSIG1 INSIG2 KLHL18 LAMC2 NDUFAF3 PGRMC1 SEC24B SREBF2 WDR6	19 interacting genes: CDK9 DHX58 DUX4 HDAC1 HDAC3 HNRNPD MYBBP1A NCOR1 NEDD4 NR2E3 OAS3 OGT RBBP4 RBBP7 RBL1 SCAP SIN3A SKIL TBL3
Entrez ID		22937	22907
HPRD ID		03300	13142
Ensembl ID		ENSG00000114650	ENSG00000132153
Uniprot IDs		B7Z6H0 Q12770	H7BXY3 Q7L2E3
PDB IDs		6M49	2DB2
Enriched GO Terms of Interacting Partners?
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