MYL12B and PNKD

Number of citations of the paper that reports this interaction (PubMedID 15188056)
12

Data Source:
HPRD (in vitro, two hybrid)

		MYL12B	PNKD
Description		myosin light chain 12B	PNKD metallo-beta-lactamase domain containing
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cytosol Brush Border Myosin II Complex Z Disc Apical Part Of Cell Extracellular Exosome Cell Cortex Region	Nucleus Mitochondrion Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Myosin Heavy Chain Binding	Hydroxyacylglutathione Hydrolase Activity Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Cell Shape	Methylglyoxal Catabolic Process To D-lactate Via S-lactoyl-glutathione Regulation Of Synaptic Transmission, Dopaminergic Regulation Of Dopamine Metabolic Process Negative Regulation Of Neurotransmitter Secretion Neuromuscular Process Controlling Posture
Pathways		EPHA-mediated growth cone collapse Sema4D induced cell migration and growth-cone collapse Smooth Muscle Contraction RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs
Drugs
Diseases
GWAS		Response to methotrexate in juvenile idiopathic arthritis ( 24709693)	Colorectal cancer ( 28960316) Colorectal cancer or advanced adenoma ( 30510241) Glycated hemoglobin levels ( 34059833) Granulocyte count ( 27863252) Height ( 28552196) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Hip circumference adjusted for BMI ( 34021172) Immature fraction of reticulocytes ( 32888494) Inflammatory bowel disease ( 28067908 23128233) Liver enzyme levels (alkaline phosphatase) ( 33972514) Monocyte count ( 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Plateletcrit ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Systolic blood pressure ( 30578418) Triglyceride levels ( 32203549) White blood cell count ( 27863252)
Interacting Genes		5 interacting genes: DAPK1 HSPB1 MYLIP NSMF PNKD	8 interacting genes: APP CNPPD1 ENO3 GMPPA KCTD9 MAGEA11 MYL12B SPEG
Entrez ID		103910	25953
HPRD ID		10095	11369
Ensembl ID		ENSG00000118680	ENSG00000127838
Uniprot IDs		O14950	A0A024R415 Q8N490
PDB IDs
Enriched GO Terms of Interacting Partners?
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