PNKD and ENO3

Number of citations of the paper that reports this interaction (PubMedID 15188056)
12

Data Source:
HPRD (in vitro, two hybrid)

		PNKD	ENO3
Description		PNKD metallo-beta-lactamase domain containing	enolase 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Membrane	Phosphopyruvate Hydratase Complex Extracellular Space Cytosol Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Hydroxyacylglutathione Hydrolase Activity Protein Binding Metal Ion Binding	Magnesium Ion Binding Phosphopyruvate Hydratase Activity Identical Protein Binding Protein-containing Complex Binding
	Biological Process	Methylglyoxal Catabolic Process To D-lactate Via S-lactoyl-glutathione Regulation Of Synaptic Transmission, Dopaminergic Regulation Of Dopamine Metabolic Process Negative Regulation Of Neurotransmitter Secretion Neuromuscular Process Controlling Posture	Glycolytic Process Aging Response To Xenobiotic Stimulus Skeletal Muscle Tissue Regeneration
Pathways			Glycolysis Gluconeogenesis
Drugs			2-phospho-D-glyceric acid Phosphoenolpyruvate 2-Phosphoglycolic Acid Phosphonoacetohydroxamic Acid
Diseases
GWAS		Colorectal cancer ( 28960316) Colorectal cancer or advanced adenoma ( 30510241) Glycated hemoglobin levels ( 34059833) Granulocyte count ( 27863252) Height ( 28552196) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Hip circumference adjusted for BMI ( 34021172) Immature fraction of reticulocytes ( 32888494) Inflammatory bowel disease ( 28067908 23128233) Liver enzyme levels (alkaline phosphatase) ( 33972514) Monocyte count ( 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Plateletcrit ( 32888494 27863252) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Systolic blood pressure ( 30578418) Triglyceride levels ( 32203549) White blood cell count ( 27863252)	Keratoconus ( 33649486) Red cell distribution width ( 32888494)
Interacting Genes		8 interacting genes: APP CNPPD1 ENO3 GMPPA KCTD9 MAGEA11 MYL12B SPEG	20 interacting genes: ALDOA APP DCTN1 DSP HSPB2 KALRN LINC01554 MAN2A2 MTMR14 NEB PGM1 PKM PNKD SGCG SNAPIN SPTB TCAP TRAPPC2 TRIM63 TTN
Entrez ID		25953	2027
HPRD ID		11369	11746
Ensembl ID		ENSG00000127838	ENSG00000108515
Uniprot IDs		A0A024R415 Q8N490	P13929
PDB IDs			2XSX
Enriched GO Terms of Interacting Partners?
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