TFG and ARHGEF16

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		TFG	ARHGEF16
Description		trafficking from ER to golgi regulator	Rho guanine nucleotide exchange factor 16
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Intracellular Membrane-bounded Organelle Endoplasmic Reticulum Exit Site	Cytosol
	Molecular Function	Protein Binding Identical Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding PDZ Domain Binding Receptor Tyrosine Kinase Binding Small GTPase Binding Cadherin Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling COPII Vesicle Coating	Cell Chemotaxis Activation Of GTPase Activity Positive Regulation Of Protein Localization To Plasma Membrane
Pathways		COPII-mediated vesicle transport Signaling by ALK fusions and activated point mutants	NRAGE signals death through JNK G alpha (12/13) signalling events CDC42 GTPase cycle RHOG GTPase cycle
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Dental caries (decayed, missing and filled tooth surfaces) ( 31533690) Response to statin therapy ( 20339536)
Interacting Genes		75 interacting genes: ANXA11 ARHGEF16 ARL15 BOLL BPIFA1 C19orf54 CEP126 CEP55 CRMP1 CRX CSTF2 DAZAP2 DVL3 ERG28 EWSR1 EYA2 FAM168A FOXH1 GBP2 GPRASP1 GRB2 HGS HNRNPF INCA1 INTS11 KHDC1 KRTAP26-1 LASP1 LENG8 MAGED1 MAPK1IP1L MED21 MED25 METTL27 MSS51 MYOT NADSYN1 NID2 OGT OXER1 PEF1 PFDN5 PIN1 PLA2G10 PLEKHG4 PLSCR1 POU2AF1 PPP1R32 PRR20A PRR20B PRR20C PRR20D PRR20E PTPN6 RBPMS RIPPLY2 RNF4 SEC24A SF3A2 SF3B4 SMUG1 SPG21 STAT5B STH TBX19 TEX37 TOMM70 TRIM25 TSSK2 UBAP2 UBE2I VPS37C WWOX ZMYM5 ZNF34	10 interacting genes: CKAP5 HNRNPH1 LASP1 LMNA LNX1 MAGED1 MAPK1IP1L TFG TNFRSF18 YWHAQ
Entrez ID		10342	27237
HPRD ID		03932	12478
Ensembl ID		ENSG00000114354	ENSG00000130762
Uniprot IDs		Q05BK6 Q92734	B3KTS4 Q5VV41
PDB IDs			1X6B
Enriched GO Terms of Interacting Partners?
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