ARHGEF16 and MAPK1IP1L

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

		ARHGEF16	MAPK1IP1L
Description		Rho guanine nucleotide exchange factor 16	mitogen-activated protein kinase 1 interacting protein 1 like
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding PDZ Domain Binding Receptor Tyrosine Kinase Binding Small GTPase Binding Cadherin Binding	Protein Binding
	Biological Process	Cell Chemotaxis Activation Of GTPase Activity Positive Regulation Of Protein Localization To Plasma Membrane
Pathways		NRAGE signals death through JNK G alpha (12/13) signalling events CDC42 GTPase cycle RHOG GTPase cycle
Drugs
Diseases
GWAS		Dental caries (decayed, missing and filled tooth surfaces) ( 31533690) Response to statin therapy ( 20339536)	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Leukoderma in response to rhododendrol ( 32558222)
Interacting Genes		10 interacting genes: CKAP5 HNRNPH1 LASP1 LMNA LNX1 MAGED1 MAPK1IP1L TFG TNFRSF18 YWHAQ	26 interacting genes: ARHGEF16 C1orf94 CEP55 DAZAP2 EIF3E EWSR1 FUBP1 HGS HNRNPUL1 KRTAP19-5 KRTAP19-7 KRTAP6-1 KRTAP6-3 LENG8 MAGED1 MSX2 PDCD6 RAMAC RBFOX2 SS18L1 SUMO1 SUMO1P1 TFG TIAL1 UBE2I VPS37C
Entrez ID		27237	93487
HPRD ID		12478	12647
Ensembl ID		ENSG00000130762	ENSG00000168175
Uniprot IDs		B3KTS4 Q5VV41	Q8NDC0
PDB IDs		1X6B
Enriched GO Terms of Interacting Partners?
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