TPTEP2-CSNK1E and ZNF618

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TPTEP2-CSNK1E	ZNF618
Description		TPTEP2-CSNK1E readthrough	zinc finger protein 618
Image			No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus Pericentric Heterochromatin
	Molecular Function		Transcription Coregulator Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process		Regulation Of Transcription, DNA-templated Positive Regulation Of Chromatin Binding
Pathways		WNT mediated activation of DVL Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Circadian Clock Anchoring of the basal body to the plasma membrane Major pathway of rRNA processing in the nucleolus and cytosol AURKA Activation by TPX2
Drugs		Seliciclib
Diseases
GWAS			Adventurousness ( 30643258) Chronotype ( 30696823) Cognitive function in longevity ( 33607172) Coronary artery aneurysm in Kawasaki disease ( 27171184) General risk tolerance (MTAG) ( 30643258) Low density lipoprotein cholesterol levels ( 30498476) Neutrophil level response to clozapine in treatment-resistant schizophrenia ( 30647433) Pulse pressure ( 30224653 30578418) Serum metabolite concentrations in chronic kidney disease ( 29545352) Systolic blood pressure ( 30578418) Tea consumption ( 31046077)
Interacting Genes		4 interacting genes: DVL3 PER2 TRIM3 ZNF618	12 interacting genes: CSNK1D CSNK1E DPPA3 G3BP2 MID1 NTAQ1 RIIAD1 TBC1D13 TPTEP2-CSNK1E UBE2I UBL5 UHRF2
Entrez ID		102800317	114991
HPRD ID			18719
Ensembl ID		ENSG00000283900	ENSG00000157657
Uniprot IDs		B3KRV2 P49674 Q5U045	Q5T7W0
PDB IDs		4HNI 4HOK
Enriched GO Terms of Interacting Partners?
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