ZNF618 and UHRF2

Number of citations of the paper that reports this interaction (PubMedID 27129234)
7

Data Source:
BioGRID (pull down, imaging technique)

		ZNF618	UHRF2
Description		zinc finger protein 618	ubiquitin like with PHD and ring finger domains 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Pericentric Heterochromatin	Heterochromatin Nucleus Nucleoplasm Pericentric Heterochromatin
	Molecular Function	Transcription Coregulator Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Metal Ion Binding	DNA Binding Ubiquitin-protein Transferase Activity Protein Binding SUMO Transferase Activity Histone Binding Metal Ion Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Positive Regulation Of Chromatin Binding	Cell Cycle Maintenance Of DNA Methylation Protein Ubiquitination Protein Sumoylation Cell Differentiation Regulation Of Cell Cycle Protein Autoubiquitination
Pathways			SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Chronotype ( 30696823) Cognitive function in longevity ( 33607172) Coronary artery aneurysm in Kawasaki disease ( 27171184) General risk tolerance (MTAG) ( 30643258) Low density lipoprotein cholesterol levels ( 30498476) Neutrophil level response to clozapine in treatment-resistant schizophrenia ( 30647433) Pulse pressure ( 30224653 30578418) Serum metabolite concentrations in chronic kidney disease ( 29545352) Systolic blood pressure ( 30578418) Tea consumption ( 31046077)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Periodontal microbiota ( 22699663)
Interacting Genes		12 interacting genes: CSNK1D CSNK1E DPPA3 G3BP2 MID1 NTAQ1 RIIAD1 TBC1D13 TPTEP2-CSNK1E UBE2I UBL5 UHRF2	40 interacting genes: ATXN1 BAX BCAR1 BCL2L1 CCND1 CD27 CDK1 CDK2 CDK4 CDK6 CTNNB1 DESI1 FANCD2 FYN H3C1 HMGB1 HMGB2 JAK3 LCK LYN MCL1 PCNP PTPRC RAD51 RBCK1 RUNX1 SKP1 SMAD4 TP53 TRIM27 TRIM8 UBE2D1 UBE2D2 UBE2D4 UBE2K UBE2W UHRF1 YY1 ZNF410 ZNF618
Entrez ID		114991	115426
HPRD ID		18719	18257
Ensembl ID		ENSG00000157657	ENSG00000147854
Uniprot IDs		Q5T7W0	Q96PU4
PDB IDs			1WY8 1Z6U 2E6S 3OLN 4PW5 4PW6 4PW7 4TVR 5YCO
Enriched GO Terms of Interacting Partners?
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