STAM2 and TIMM8A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		STAM2	TIMM8A
Description		signal transducing adaptor molecule 2	translocase of inner mitochondrial membrane 8A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Endocytic Vesicle Early Endosome Membrane ESCRT-0 Complex Intracellular Membrane-bounded Organelle	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space
	Molecular Function	Protein Binding Phosphatidylinositol Binding Ubiquitin Binding	Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Signal Transduction Protein Transport Macroautophagy Multivesicular Body Assembly	Nervous System Development Protein Insertion Into Mitochondrial Inner Membrane
Pathways		EGFR downregulation Ub-specific processing proteases Negative regulation of MET activity Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis InlB-mediated entry of Listeria monocytogenes into host cell RHOU GTPase cycle Endosomal Sorting Complex Required For Transport (ESCRT)	Mitochondrial protein import
Drugs
Diseases
GWAS		Adverse response to chemotherapy in breast cancer (alopecia) ( 24025145) Metabolic syndrome ( 31170924) Pulse pressure ( 30224653)
Interacting Genes		38 interacting genes: ABI2 ARRDC3 ATXN1 CBX5 CDC7 DAZAP2 EGFR EPS15 FAM189A2 HGS ITCH JAK1 JAK2 JAK3 KLHL42 L3MBTL2 LCP2 LITAF MAP3K1 PHF10 PLEKHB2 PTPN1 RNF11 SH2D4A STAMBP TIMM8A TYK2 UBC UBE2D1 UBE2D2 UBE2D3 UBE2H UBQLN1 UBQLN4 USP8 VPS37C XRN1 ZC3H10	9 interacting genes: ARID3A C1QTNF2 CAVIN3 KRT15 OIP5 STAM STAM2 TIMM13 TRAF6
Entrez ID		10254	1678
HPRD ID		05876	02287
Ensembl ID		ENSG00000115145	ENSG00000126953
Uniprot IDs		O75886	A0A2R8YDA8 O60220
PDB IDs		1X2Q 1X5B 2L0T 5CRV 5IXF
Enriched GO Terms of Interacting Partners?
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