Description |
cyclin dependent kinase 5 |
mitogen-activated protein kinase 10 |
Image |
|
|
GO Annotations |
Cellular Component |
|
|
Molecular Function |
|
|
Biological Process |
|
|
Pathways |
|
|
Drugs |
|
- Minocycline
- Pyrazolanthrone
- Cyclohexyl-{4-[5-(3,4-Dichlorophenyl)-2-Piperidin-4-Yl-3-Propyl-3h-Imidazol-4-Yl]-Pyrimidin-2-Yl}Amine
- Cyclopropyl-{4-[5-(3,4-Dichlorophenyl)-2-[(1-Methyl)-Piperidin]-4-Yl-3-Propyl-3h-Imidazol-4-Yl]-Pyrimidin-2-Yl}Amine
- 9-(4-Hydroxyphenyl)-2,7-Phenanthroline
- Phosphoaminophosphonic Acid-Adenylate Ester
- N-(tert-butyl)-4-[5-(pyridin-2-ylamino)quinolin-3-yl]benzenesulfonamide
- N-BENZYL-4-[4-(3-CHLOROPHENYL)-1H-PYRAZOL-3-YL]-1H-PYRROLE-2-CARBOXAMIDE
- N-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-2-fluorobenzamide
- 4-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}-N-ethylpiperidine-1-carboxamide
- (3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-[(E)-2-phenylethenyl]-1H-indole-2,3-dione 3-oxime
- (3E)-5-fluoro-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-1H-indole-2,3-dione 3-oxime
- (3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-phenyl-1H-indole-2,3-dione 3-oxime
- 5-bromo-N-(3-chloro-2-(4-(prop-2-ynyl)piperazin-1-yl)phenyl)furan-2-carboxamide
- N-cyclohexyl-4-imidazo[1,2-a]pyridin-3-yl-N-methylpyrimidin-2-amine
- N-{2'-[(4-FLUOROPHENYL)AMINO]-4,4'-BIPYRIDIN-2-YL}-4-METHOXYCYCLOHEXANECARBOXAMIDE
- 2-{4-[(4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]piperidin-1-yl}-N-methylacetamide
- 1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline
- Fostamatinib
- Halicin
|
Diseases |
|
|
GWAS |
|
- Cleft lip with or without cleft palate x maternal periconceptional smoking interaction (parent of origin effect) ( 31372216)
- Cobalt levels ( 26025379)
- Diisocyanate-induced asthma ( 25918132)
- Gait speed in old age ( 28077804)
- Liver enzyme levels (alanine transaminase) ( 33972514 22001757)
- Multiple sclerosis ( 31604244)
- Peripheral artery disease ( 25009551)
- Response to cytidine analogues (gemcitabine) ( 24483146)
- Triglyceride levels ( 32203549 32154731)
|
Interacting Genes |
82 interacting genes:
AATK
ABL1
ACTN1
ALAS1
AMPH
APP
BAG6
CABLES1
CABLES2
CCND2
CCND3
CCNG1
CCNI
CDC25A
CDC25B
CDC25C
CDC37
CDK16
CDK5R1
CDK5R2
CDK5RAP1
CDK5RAP2
CDKN1B
CHN1
CSNK1D
CTNNB1
DAB1
DCX
DNM1
ERBB3
EZR
FSD1
FYN
FZR1
GAK
GRIN2A
GSK3B
H1-0
H1-1
H1-5
HTRA2
KIF26B
LMTK2
MAP2K1
MAPK10
MAPT
MAST1
MBP
MEF2A
MEOX2
MIR9-1HG
NDEL1
NEDD4
NEDD4L
NES
PAK1
PCNA
PIKFYVE
PIP5K1C
PPARG
PPP1R1B
PPP1R2
PRKN
PSEN1
PTPN2
PURA
RB1
RNF32
RPL34
SET
SPDYA
SPDYE4
SRC
STX1A
STXBP1
SYN1
SYNJ1
TLN1
TP53
TRIM59
WASF1
YBX3
|
40 interacting genes:
APP
ARRB1
ARRB2
ATF2
BCL2L11
CDK5
CDKN1B
CDKN2A
CDKN2C
CEP290
CREBBP
DUSP10
DUSP16
DUSP9
ELK1
FBXO7
GTF3C1
HAX1
HDAC9
HNRNPK
HRAS
JUN
KIF26A
KIF5A
LDHA
MAP2K4
MAPK8IP2
MAPK8IP3
MAPKBP1
MAPT
MCL1
PKMYT1
PLIN2
RELA
SH3BP5
STMN2
TNIP1
TP53
UBE3A
UNC119
|
Entrez ID |
1020 |
5602 |
HPRD ID |
00449 |
04207 |
Ensembl ID |
ENSG00000164885
|
ENSG00000109339
|
Uniprot IDs |
A0A090N7W4
A0A0S2Z355
Q00535
|
A0A1P0B7D2
A0A286YEQ7
A0A286YES0
A0A286YF02
A0A286YF97
A0A286YFD7
A0A286YFN2
D6RCB1
D6RJF9
F8W9R5
I6L9F3
P53779
Q499Y8
|
PDB IDs |
1H4L
1LFR
1UNG
1UNH
1UNL
3O0G
4AU8
|
1JNK
1PMN
1PMU
1PMV
2B1P
2EXC
2O0U
2O2U
2OK1
2P33
2R9S
2WAJ
2ZDT
2ZDU
3CGF
3CGO
3DA6
3FI2
3FI3
3FV8
3G90
3G9L
3G9N
3KVX
3OXI
3OY1
3PTG
3RTP
3TTI
3TTJ
3V6R
3V6S
4H36
4H39
4H3B
4KKE
4KKG
4KKH
4U79
4W4V
4W4W
4W4X
4W4Y
4WHZ
4X21
4Y46
4Y5H
4Z9L
6EKD
6EMH
6EQ9
7KSI
7KSJ
7KSK
|
Enriched GO Terms of Interacting Partners? |
|
|
Tagcloud ? |
|
|
Tagcloud (Difference) ? |
|
|
Tagcloud (Intersection) ? |
|