TMEM239 and FBXL19

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM239	FBXL19
Description		transmembrane protein 239	F-box and leucine rich repeat protein 19
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	Protein Binding	Transcription Coregulator Activity Protein Binding Zinc Ion Binding Histone Demethylase Activity Unmethylated CpG Binding
	Biological Process		Regulation Of Transcription By RNA Polymerase II Protein Demethylation Histone Demethylation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31451708) Pulse pressure ( 30224653) White matter integrity ( 23218918)	Diastolic blood pressure ( 28135244 27841878) Mean corpuscular volume ( 27863252) Psoriasis ( 25903422 20953189 25574825 23143594) Psoriasis vulgaris ( 26626624) Psoriatic arthritis ( 26626624) Pulse pressure ( 27841878)
Interacting Genes		67 interacting genes: AQP6 ATF7 CD79A CLDN20 CLRN1 COQ8A CREB3L1 CREB3L3 CXCL16 DARS2 DCUN1D1 EBP EMP1 FAM174A FBXL19 FFAR2 FGD2 FKBP7 FTHL17 FXYD6 GJA8 GPR101 GPR151 GPR42 LENG1 LNX1 MFSD14B MIEF2 MPP1 MS4A3 MTIF3 MTURN MYG1 NTAQ1 OCIAD1 ODF4 OTULIN PDCD1LG2 PNKP POLI PSCA REEP2 RETREG3 S100B SCAND1 SCN3B SDCBP SENP2 SERINC2 SLC10A1 SLC10A6 SLC18A1 SLC34A2 SLC35C2 SNX1 SNX2 SPG21 SSMEM1 SYT16 TBRG4 TIMMDC1 TMEM248 TMEM31 TMX2 TRHR UBASH3A USP5	12 interacting genes: ABI1 ABI2 CBFA2T2 CREBBP DGAT2L6 EFHC2 NCK2 RPRM SORBS3 TMEM239 TRIM27 TRIM29
Entrez ID		100288797	54620
HPRD ID			12366
Ensembl ID		ENSG00000198326	ENSG00000099364
Uniprot IDs		Q8WW34	H3BVB1 Q6PCT2
PDB IDs			6ASB
Enriched GO Terms of Interacting Partners?
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