FBXL19 and TRIM29

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		FBXL19	TRIM29
Description		F-box and leucine rich repeat protein 19	tripartite motif containing 29
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GO Annotations	Cellular Component	Cytosol SCF Ubiquitin Ligase Complex	Lysosome Adherens Junction
	Molecular Function	Transcription Coregulator Activity Protein Binding Zinc Ion Binding Histone Demethylase Activity Unmethylated CpG Binding	P53 Binding Protein Binding Zinc Ion Binding Identical Protein Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Regulation Of Transcription By RNA Polymerase II Protein Demethylation Histone Demethylation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Negative Regulation Of Transcription By RNA Polymerase II Innate Immune Response Cell-cell Adhesion Negative Regulation Of Protein Localization To Nucleus
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Interferon gamma signaling
Drugs
Diseases
GWAS		Diastolic blood pressure ( 28135244 27841878) Mean corpuscular volume ( 27863252) Psoriasis ( 25903422 20953189 25574825 23143594) Psoriasis vulgaris ( 26626624) Psoriatic arthritis ( 26626624) Pulse pressure ( 27841878)	Corneal curvature ( 22969067) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Resistance to antihypertensive treatment in hypertension ( 31545351) Retinal detachment or retinal break ( 31816047) Stroke (pediatric) ( 22990015)
Interacting Genes		12 interacting genes: ABI1 ABI2 CBFA2T2 CREBBP DGAT2L6 EFHC2 NCK2 RPRM SORBS3 TMEM239 TRIM27 TRIM29	56 interacting genes: ACTN3 ANKS1A ATM ATP1A3 CARD9 CCDC57 CDC34 CEP70 CRACR2A DISC1 DMRT1 FBF1 FBXL19 FXR2 GATA1 GCC1 GOLGA2 GTF2E1 H4C1 HCLS1 HDAC9 HINT1 HNRNPLL IKBKG JAKMIP2 KAT5 KRT35 LZTS2 MAD1L1 MAPKAPK2 MED7 MID2 MLH1 MSH2 MTUS2 MYO15B NFKBID POLR2D POLR2E PRICKLE3 PRKCA RNF8 SHOX2 SMAD9 SNAPC1 SP100 TAX1BP3 TRIM11 TRIM23 TRIM27 TRIP6 TSGA10 UBE2C UBE2E1 UBE2I VIM
Entrez ID		54620	23650
HPRD ID		12366	10280
Ensembl ID		ENSG00000099364	ENSG00000137699
Uniprot IDs		H3BVB1 Q6PCT2	A0A024R3J1 B7Z5V5 B7Z8U9 E9PRL4 Q14134
PDB IDs		6ASB	2CSV
Enriched GO Terms of Interacting Partners?
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