FRAT1 and GPRASP2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

		FRAT1	GPRASP2
Description		FRAT regulator of WNT signaling pathway 1	G protein-coupled receptor associated sorting protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Intracellular Membrane-bounded Organelle	Nucleus Cytoplasm
	Molecular Function	Protein Binding	Amyloid-beta Binding G Protein-coupled Receptor Binding Protein Binding
	Biological Process	Canonical Wnt Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway	Hematopoietic Stem Cell Homeostasis
Pathways		Beta-catenin phosphorylation cascade Disassembly of the destruction complex and recruitment of AXIN to the membrane
Drugs
Diseases
GWAS		Liver enzyme levels (alanine transaminase) ( 33972514) Lymphocyte counts ( 32888494) White blood cell count ( 32888494)
Interacting Genes		13 interacting genes: DVL1 GPRASP2 GRN GSK3B KCNK5 KRT18 LAMC3 LMAN2 LTBP4 PLSCR1 PSMA3 RABEP2 TDRD7	52 interacting genes: ADRB1 ARHGEF6 BARD1 CALCR CAVIN3 CBX8 CCDC146 CEP126 CFAP206 CHRM1 CHRM2 DISC1 EFCAB3 FAM124B FCHSD2 FOXD4L1 FRAT1 GADD45GIP1 HAP1 HRH2 HTR7 HTT LRIF1 MBD3L2 MICU2 MYOT NOL4L-DT PIH1D2 PLAC9 PRPF3 PTN RABGEF1 REX1BD RHPN1 RNF8 RPS6KA5 RTL10 SAPCD2 SEZ6L SH2D4A SREK1 STMN2 TBRG4 TCF25 TSPOAP1 TTC23 TXN TXN2 USP20 ZC2HC1C ZFYVE26 ZNF688
Entrez ID		10023	114928
HPRD ID		03935	06612
Ensembl ID		ENSG00000165879	ENSG00000158301
Uniprot IDs		Q92837	B3KW05 Q96D09
PDB IDs		1GNG 3ZRK 3ZRL 3ZRM 4AFJ 5OY4
Enriched GO Terms of Interacting Partners?
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