KCNE3 and RASSF1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		KCNE3	RASSF1
Description		potassium voltage-gated channel subfamily E regulatory subunit 3	Ras association domain family member 1
Image
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Dendrite Vesicle Neuronal Cell Body Membrane Perikaryon Membrane Raft Basolateral Part Of Cell	Spindle Pole Nucleus Cytoplasm Microtubule Organizing Center Microtubule Microtubule Cytoskeleton
	Molecular Function	Delayed Rectifier Potassium Channel Activity Protein Binding Potassium Channel Regulator Activity Transmembrane Transporter Binding Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization	Protein Binding Zinc Ion Binding
	Biological Process	Sodium Ion Transport Cellular Chloride Ion Homeostasis Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Regulation Of Heart Rate By Cardiac Conduction Potassium Ion Export Across Plasma Membrane Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Positive Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Potassium Ion Export Across Plasma Membrane Negative Regulation Of Voltage-gated Potassium Channel Activity Negative Regulation Of Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential	Cell Cycle Signal Transduction Ras Protein Signal Transduction Regulation Of Cell Cycle Regulation Of Microtubule Cytoskeleton Organization
Pathways		Phase 3 - rapid repolarisation Phase 2 - plateau phase
Drugs		Enflurane Promethazine Miconazole
Diseases
GWAS		Corneal astigmatism ( 22144915) Neuritic plaque ( 31497858)	Basophil percentage of white cells ( 32888494) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) High light scatter reticulocyte count ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Schizophrenia ( 28991256 30285260) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		10 interacting genes: C11orf68 EEF1A1 GAPDH GOLM1 KIF5A LRIF1 POLA2 QARS1 RASSF1 SLC44A1	73 interacting genes: AKT1 ARAF ATM ATP2B4 ATR ATRX AURKA AURKB BANF1 BRAF C7orf25 C8orf33 CCND2 CCNE1 CDC20 CDK4 CDK6 CDKN2A CDKN2B CLNK CNKSR1 DAXX DDB1 E4F1 EPHA2 ERBB2 EXOSC8 FGFR4 FZR1 GLIS2 GRM1 HRAS IGFBP5 KAT2A KCNE3 KDELR2 KDM1A LARS2 LATS2 MAP1B MAP1S MAP2K3 MAP2K6 MAPK8 MDM2 MET MOAP1 MST1 MYC NF2 NUDT10 PFDN5 PRKDC RAF1 RASSF5 RELA RHOA RHOU SMARCA4 STK11 STK4 SUV39H1 SUV39H2 TEAD2 TERT TMEM115 TMEM158 TNFRSF10A TNFRSF1A TSC1 TUBB TUBG1 XPA
Entrez ID		10008	11186
HPRD ID		07256	05470
Ensembl ID		ENSG00000175538	ENSG00000068028
Uniprot IDs		Q6IAE6 Q9Y6H6	Q9NS23
PDB IDs		2NDJ 6V00 6V01	2KZU
Enriched GO Terms of Interacting Partners?
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