HiPPIP
  • Home
  • About
  • SZ Genes
  • People
  • Help
  • Advanced Search

CD3D

Description CD3d molecule
Image
GO Annotations Cellular Component
  • Cytoplasm
  • Plasma Membrane
  • External Side Of Plasma Membrane
  • Integral Component Of Membrane
  • Clathrin-coated Endocytic Vesicle Membrane
  • T Cell Receptor Complex
  • Alpha-beta T Cell Receptor Complex
Molecular Function
  • Transmembrane Signaling Receptor Activity
  • Protein Binding
  • Identical Protein Binding
Biological Process
  • Adaptive Immune Response
  • Cell Surface Receptor Signaling Pathway
  • Positive Thymic T Cell Selection
Pathways
  • Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
  • Downstream TCR signaling
  • Phosphorylation of CD3 and TCR zeta chains
  • Translocation of ZAP-70 to Immunological synapse
  • Generation of second messenger molecules
  • PD-1 signaling
  • Cargo recognition for clathrin-mediated endocytosis
  • Clathrin-mediated endocytosis
Drugs
  • Muromonab
  • Blinatumomab
Diseases
GWAS
  • Pulse pressure ( 27841878)
Interacting Genes 12 interacting genes: AP2M1 CANX CD247 CD3E CD3G CD8A CD8B HERPUD1 KCNA3 SGTB TRA TRB
Entrez ID 915
HPRD ID 01730
Ensembl ID ENSG00000167286
Uniprot IDs B0YIY4 P04234
PDB IDs 1XIW 6JXR
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025