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THOC1 and WDR77
Data Source:
BioGRID
(two hybrid)
THOC1
WDR77
Description
THO complex 1
WD repeat domain 77
Image
GO Annotations
Cellular Component
Transcription Export Complex
THO Complex
THO Complex Part Of Transcription Export Complex
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Matrix
Nuclear Speck
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Methylosome
Pole Plasm
Molecular Function
DNA Binding
RNA Binding
Protein Binding
Protein Binding
Methyl-CpG Binding
Nuclear Receptor Coactivator Activity
Biological Process
Regulation Of DNA Recombination
RNA Processing
RNA Export From Nucleus
MRNA Export From Nucleus
Apoptotic Process
Signal Transduction
RNA Splicing
MRNA 3'-end Processing
Replication Fork Processing
Regulation Of DNA-templated Transcription, Elongation
Positive Regulation Of DNA-templated Transcription, Elongation
Viral MRNA Export From Host Cell Nucleus
Negative Regulation Of Isotype Switching To IgA Isotypes
Negative Regulation Of DNA Damage Checkpoint
Spliceosomal SnRNP Assembly
Regulation Of Transcription By RNA Polymerase II
Pole Plasm Assembly
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Transcription, DNA-templated
Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development
Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Pathways
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
snRNP Assembly
RMTs methylate histone arginines
Drugs
Diseases
GWAS
Bipolar disorder (
20351715
)
Bipolar disorder or major depressive disorder (
20351715
)
Height (
31562340
)
Menarche (age at onset) (
29773799
)
Triglyceride levels (
32203549
)
Interacting Genes
26 interacting genes:
AGR2
AKAP9
BHLHB9
CTAG1A
CTAG1B
DHX8
EXOC5
FRA10AC1
IK
MAGEB4
MOAP1
MTNR1B
NEDD4
PAX6
PPP1R12C
RABGEF1
RB1
REL
SAP30BP
SF3B2
TADA2A
TRIM27
TRIM54
USHBP1
WDR77
ZMYND12
44 interacting genes:
AQR
BAG2
CDK19
CDK8
CLNS1A
CREBBP
CTDP1
GLI1
GPKOW
H2AC21
HNRNPM
LSM3
NKX3-1
PCBP2
PPIL1
PPP1R8
PQBP1
PRKG1
PRKG2
PRMT5
QKI
RBM5
RIOK1
SAP30BP
SF1
SF3A1
SF3B4
SIRT7
SMAD1
SMYD1
SNRPB
SNRPC
SNRPD1
SNRPD2
SNRPD3
SNRPE
SNRPF
SUZ12
THOC1
TOE1
YWHAB
YWHAQ
ZMYND19
ZNF207
Entrez ID
9984
79084
HPRD ID
09498
14387
Ensembl ID
ENSG00000079134
ENSG00000116455
Uniprot IDs
Q96FV9
A0A024R0H7
Q9BQA1
PDB IDs
1WXP
4GQB
4X60
4X61
4X63
5C9Z
5EMJ
5EMK
5EML
5EMM
5FA5
6CKC
6K1S
6RLL
6RLQ
6UXX
6UXY
6V0N
6V0O
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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